Pygo2tm1.1Kba
Targeted Allele Detail
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| Symbol: |
Pygo2tm1.1Kba |
| Name: |
pygopus 2; targeted mutation 1.1, Konrad Basler |
| MGI ID: |
MGI:5518423 |
| Synonyms: |
Pygo2A342E |
| Gene: |
Pygo2 Location: Chr3:89337521-89342435 bp, + strand Genetic Position: Chr3, 39.12 cM
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| Alliance: |
Pygo2tm1.1Kba page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:198562
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| Parent Cell Line: |
iTL BA1 (ES Cell)
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| Strain of Origin: |
(C57BL/6NTac x 129S6/SvEvTac)F1
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| Allele Type: |
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Targeted |
| Mutations: |
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Insertion, Nucleotide substitutions
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Mutation details: Nucleotide substitutions (CC to AG) result in the amino acid substitution of glutamic acid for alanine at position 342 (A342E). Flp-mediated recombination removed an FRT-flanked neomycin resistance cassette inserted upstream of the modified exon.
(J:198562)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Pygo2 Mutation: |
24 strains or lines available
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| Original: |
J:198562 Cantu C, et al., The Pygo2-H3K4me2/3 interaction is dispensable for mouse development and Wnt signaling-dependent transcription. Development. 2013 Jun;140(11):2377-86 |
| All: |
2 reference(s) |
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Analysis Tools
