Tg(Hoxa5-cre)444CLjea
Transgene Detail
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| Symbol: |
Tg(Hoxa5-cre)444CLjea |
| Name: |
transgene insertion 444C, Lucie Jeannotte |
| MGI ID: |
MGI:5518946 |
| Synonyms: |
Tg(7.1kb Hoxa5-cre)Ljea |
| Transgene: |
Tg(Hoxa5-cre)444CLjea Location: unknown
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| Alliance: |
Tg(Hoxa5-cre)444CLjea page
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| Transgene Type: |
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Transgenic (Recombinase) |
| Mutation: |
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Insertion
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Tg(Hoxa5-cre)444CLjea expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| Not Specified |
Hoxa5 |
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Mutation details: A 5 kb genomic fragment of Hoxa5 (containing the temporal (T) control region, the brachial spinal cord (BSC) enhancer, proximal Hoxa5 promoter, both exons and the intron of Hoxa5) drives cre epxression in this transgene. An IRES-EGFPcre cassette was inserted into exon 1 of Hoxa5 downstream of the translation initiation codon. A 2.1 kb fragment containing the mesodermal (MES) enhancer was added at the 3' end of the construct to produce the 7.1 Hoxa5/Cre transgene. Nine founder lines were obtained andLine 444C was established. This line has 2 copies of the transgene.
(J:207917)
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Generation of Tg(Hoxa5-cre)444CLjea. |
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Hoxa5
(species not specified)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:207917 Berube-Simard FA, et al., Hoxa5/Cre transgenic mice: novel tools for regional deletion along the anterior-posterior axis. Genesis. 2014 Feb;52(2):149-56 |
| All: |
2 reference(s) |
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Analysis Tools
