Lin28a<tm2.1Gqda> Targeted Allele Detail MGI Mouse (MGI:5520055)

Lin28a^tm2.1Gqda
Targeted Allele Detail

Summary

Symbol:	Lin28a^tm2.1Gqda
Name:	lin-28 homolog A; targeted mutation 2.1, George Q Daley
MGI ID:	MGI:5520055
Gene:	Lin28a Location: Chr4:133730641-133746152 bp, - strand Genetic Position: Chr4, 66.5 cM
Alliance:	Lin28a^tm2.1Gqda page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:101977
Parent Cell Line:	v6.5 (ES Cell)
Strain of Origin:	(C57BL/6 x 129S4/SvJae)F1

Mutation
description

Allele Type:		Targeted (Conditional ready, No functional change)
Mutation:		Insertion
		Mutation details: A loxP site was inserted upstream of exon 2. An FRT flanked neo cassette with a 5' loxP site was inserted downstream of exon 2 via homologous recombination. FLP-mediated recombination removed the neomycin cassette. (J:101977)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any Lin28a Mutation:	76 strains or lines available

Notes

The targeting vector used to generate this allele was co-injected with the targeting vector used to generate Lin28b^tm2.1Gqda.

References

Original:	J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:	6 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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