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Psmb11tm1.1(icre)Yout
Targeted Allele Detail
Summary
Symbol: Psmb11tm1.1(icre)Yout
Name: proteasome (prosome, macropain) subunit, beta type, 11; targeted mutation 1.1, Yousuke Takahama
MGI ID: MGI:5521209
Synonyms: beta5t-Cre
Gene: Psmb11  Location: Chr14:54862767-54867013 bp, + strand  Genetic Position: Chr14, 27.87 cM
Alliance: Psmb11tm1.1(icre)Yout page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:197387
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129 x C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout, Recombinase)
Mutations:    Insertion, Intragenic deletion
 
Psmb11tm1.1(icre)Yout expression driven by 1 gene
 
Mutation details: A codon improved cre cDNA and FRT flanked PGKK-neo cassette in reverse orientation were inserted in place of most of the sole exon. The PGK- neo was subsequently removed from properly targeted mice by flp recombinase expression. (J:197387)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Psmb11 (mouse)
Summary of all recombinase alleles driven by Psmb11.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Psmb11 Mutation:  11 strains or lines available
References
Original:  J:197387 Ohigashi I, et al., Aire-expressing thymic medullary epithelial cells originate from beta5t-expressing progenitor cells. Proc Natl Acad Sci U S A. 2013 Jun 11;110(24):9885-90
All:  8 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory