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Tg(Slc32a1-cre)65Kzy
Transgene Detail
Summary
Symbol: Tg(Slc32a1-cre)65Kzy
Name: transgene insertion 65, Kazuhiro Yamakawa
MGI ID: MGI:5523786
Synonyms: Tg65, VGAT-Cre, Viaat-Cre
Transgene: Tg(Slc32a1-cre)65Kzy  Location: unknown  
Alliance: Tg(Slc32a1-cre)65Kzy page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Slc32a1-cre)65Kzy expression driven by 1 gene
 
Mutation details: Red/ET recombination was used to insert the sequences encoding cre recombinase, the SV40 poly(A) signal, and a kanamycin resistance gene at the ATG (translational initiation site) of the Slc32a1 (Vgat or Viaat) locus contained in RP23-392-P11 BAC clone derived from C57BL/6 mouse genomic DNA. The purified construct was injected into pronuclei of C57BL/6 oocytes. Transgenic line 65 was used in further analyses. (J:202863)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Slc32a1 (mouse)
Summary of all recombinase alleles driven by Slc32a1.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:202863 Ogiwara I, et al., Nav1.1 haploinsufficiency in excitatory neurons ameliorates seizure-associated sudden death in a mouse model of Dravet syndrome. Hum Mol Genet. 2013 Dec 1;22(23):4784-804
All:  15 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory