About   Help   FAQ
Ano6tm1.1Naga
Targeted Allele Detail
Summary
Symbol: Ano6tm1.1Naga
Name: anoctamin 6; targeted mutation 1.1, Shigekazu Nagata
MGI ID: MGI:5538269
Synonyms: TMEM16Fflox
Gene: Ano6  Location: Chr15:95688724-95872632 bp, + strand  Genetic Position: Chr15, 50.66 cM
Alliance: Ano6tm1.1Naga page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:198369
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation details: A loxP site was inserted upstream of exon 2. An FRT-flanked neomycin cassette with a 3' loxP site was inserted downstream of exon 2. Flp-mediated recombination removed the neomycin resistance cassette and left exon 3 floxed. (J:198369)
Generation of the Ano6tm1.1Naga allele
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ano6 Mutation:  83 strains or lines available
References
Original:  J:198369 Suzuki J, et al., Calcium-dependent phospholipid scramblase activity of TMEM16 protein family members. J Biol Chem. 2013 May 10;288(19):13305-16
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory