About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
Assay type: RNA in situ
MGI Accession ID: MGI:5538984
Gene symbol: Wt1
Gene name: WT1 transcription factor
Probe: NIA clone H3139H04
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen GUDMAP:62: embryonic day 10.5 (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS17: gonad primordium Ambiguous GUDMAP:62
TS17: mesonephros Present GUDMAP:62
TS17: metanephric mesenchyme Present GUDMAP:62
TS17: nephric duct, metanephric portion Absent GUDMAP:62
TS17: mesonephros mesenchyme Present GUDMAP:62
TS17: nephric duct, mesonephric portion Absent GUDMAP:62
TS17: genitourinary system mesenchyme Absent GUDMAP:62
TS17: genitourinary system Present GUDMAP:62

Specimen GUDMAP:7467: postnatal adult (more )
Note: Labeling was visualized using NBT/BCIP.
Structure Level Pattern Image Note
TS28: ovary Present GUDMAP:7467 signal in germinal cells of follicles is strong in primary follicles and weakens as the follicle matures.
TS28: ovary primary follicle Present GUDMAP:7467
TS28: follicle cell of primary follicle Present GUDMAP:7467
TS28: follicle cell of secondary follicle Present GUDMAP:7467
TS28: oviduct Present GUDMAP:7467
TS28: rest of oviduct Present GUDMAP:7467
TS28: epithelial layer of rest of oviduct Present GUDMAP:7467
TS28: oviduct infundibulum Present GUDMAP:7467
TS28: epithelial layer of infundibulum Present GUDMAP:7467
TS28: surface epithelium of ovary Present GUDMAP:7467
TS28: ovary tertiary follicle Present GUDMAP:7467
TS28: follicle cell of tertiary follicle Present GUDMAP:7467
TS28: ovary secondary follicle Present GUDMAP:7467
TS28: germinal cell of mature follicle Present GUDMAP:7467
TS28: ovary ruptured follicle Present GUDMAP:7467
TS28: germinal cell of ruptured follicle Present GUDMAP:7467
TS28: granulosa of ruptured follicle Present GUDMAP:7467
TS28: corpus luteum Absent GUDMAP:7467

Specimen GUDMAP:14088: embryonic day 15.5 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS23: metanephros Present GUDMAP:14088
TS23: urinary system Present GUDMAP:14088
TS23: nephrogenic zone Present GUDMAP:14088
TS23: renal cortex Present GUDMAP:14088
TS23: cap mesenchyme Present GUDMAP:14088
TS23: nephrogenic interstitium Present GUDMAP:14088
TS23: pretubular aggregate Present GUDMAP:14088
TS23: renal vesicle Present GUDMAP:14088
TS23: comma-shaped body Present GUDMAP:14088
TS23: s-shaped body Present GUDMAP:14088
TS23: capillary loop renal corpuscle Present GUDMAP:14088
TS23: maturing renal corpuscle Present GUDMAP:14088
TS23: proximal renal vesicle Present GUDMAP:14088
TS23: lower limb of comma-shaped body Present GUDMAP:14088
TS23: proximal segment of s-shaped body Present GUDMAP:14088
TS23: visceral epithelium of s-shaped body Present GUDMAP:14088
TS23: parietal epithelium of s-shaped body Present GUDMAP:14088
TS23: visceral epithelium of capillary loop renal corpuscle Present GUDMAP:14088
TS23: maturing glomerular tuft Present GUDMAP:14088
TS23: visceral epithelium of maturing renal corpuscle Present GUDMAP:14088
TS23: ureteric tip Absent GUDMAP:14088
TS23: ureteric tree terminal branch excluding tip itself Absent GUDMAP:14088
TS23: renal connecting segment of renal vesicle Absent GUDMAP:14088
TS23: upper limb of comma-shaped body Absent GUDMAP:14088
TS23: renal connecting segment of comma-shaped body Absent GUDMAP:14088
TS23: renal connecting tubule of s-shaped body Absent GUDMAP:14088
TS23: distal segment of s-shaped body Absent GUDMAP:14088
TS23: medial segment of s-shaped body Absent GUDMAP:14088
TS23: associated interstitium of capillary loop renal corpuscle Absent GUDMAP:14088
TS23: presumptive endothelium of capillary loop renal corpuscle Absent GUDMAP:14088
TS23: presumptive mesangium of capillary loop renal corpuscle Absent GUDMAP:14088
TS23: glomerular capillary system of maturing glomerular tuft Absent GUDMAP:14088
TS23: glomerular mesangium of maturing glomerular tuft Absent GUDMAP:14088
TS23: Bowman's capsule of maturing renal corpuscle Absent GUDMAP:14088
TS23: juxtaglomerular arteriole Absent GUDMAP:14088
TS23: cortical renal tubule Absent GUDMAP:14088
TS23: cortical collecting duct Absent GUDMAP:14088
TS23: renal cortical vasculature Absent GUDMAP:14088
TS23: parietal epithelium of capillary loop renal corpuscle Present GUDMAP:14088
TS23: renal medulla Present GUDMAP:14088
TS23: renal medullary interstitium Present Regionally restricted GUDMAP:14088 Regional expression in renal medullary interstitium adjacent to medullary collecting duct.
TS23: renal cortical interstitium Present Regionally restricted GUDMAP:14088
TS23: medullary collecting duct Absent GUDMAP:14088
TS23: immature loop of Henle Absent GUDMAP:14088
TS23: renal medullary vasculature Absent GUDMAP:14088
TS23: pelvic urothelial lining Absent GUDMAP:14088
TS23: pelvic smooth muscle Absent GUDMAP:14088
TS23: urothelium of ureter Absent GUDMAP:14088
TS23: ureteral mesenchyme subepithelial layer Absent GUDMAP:14088
TS23: ureteral smooth muscle layer Absent GUDMAP:14088

Specimen GUDMAP:14089: postnatal day 0 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS27: urinary system Present GUDMAP:14089
TS27: metanephros Present GUDMAP:14089
TS27: nephrogenic zone Present GUDMAP:14089
TS27: nephrogenic interstitium Present GUDMAP:14089
TS27: cap mesenchyme Present GUDMAP:14089
TS27: pretubular aggregate Present GUDMAP:14089
TS27: renal cortex Present GUDMAP:14089
TS27: renal medulla Ambiguous GUDMAP:14089
TS27: renal vesicle Present GUDMAP:14089
TS27: comma-shaped body Present GUDMAP:14089
TS27: s-shaped body Present GUDMAP:14089
TS27: capillary loop renal corpuscle Present GUDMAP:14089
TS27: maturing renal corpuscle Present GUDMAP:14089
TS27: mature renal corpuscle Present GUDMAP:14089
TS27: parietal epithelium of capillary loop renal corpuscle Present GUDMAP:14089
TS27: visceral epithelium of capillary loop renal corpuscle Present GUDMAP:14089
TS27: maturing glomerular tuft Present GUDMAP:14089
TS27: visceral epithelium of maturing renal corpuscle Present GUDMAP:14089
TS27: glomerular tuft Present GUDMAP:14089
TS27: visceral epithelium of mature renal corpuscle Present GUDMAP:14089
TS27: proximal segment of s-shaped body Present GUDMAP:14089
TS27: visceral epithelium of s-shaped body Present GUDMAP:14089
TS27: parietal epithelium of s-shaped body Present GUDMAP:14089
TS27: proximal renal vesicle Present GUDMAP:14089
TS27: renal connecting segment of renal vesicle Absent GUDMAP:14089
TS27: renal connecting tubule of s-shaped body Absent GUDMAP:14089
TS27: distal segment of s-shaped body Absent GUDMAP:14089
TS27: medial segment of s-shaped body Absent GUDMAP:14089
TS27: ureteric tree terminal branch excluding tip itself Absent GUDMAP:14089
TS27: ureteric tip Absent GUDMAP:14089
TS27: associated interstitium of capillary loop renal corpuscle Absent GUDMAP:14089
TS27: presumptive endothelium of capillary loop renal corpuscle Absent GUDMAP:14089
TS27: presumptive mesangium of capillary loop renal corpuscle Absent GUDMAP:14089
TS27: glomerular capillary system of maturing glomerular tuft Absent GUDMAP:14089
TS27: glomerular mesangium of maturing glomerular tuft Absent GUDMAP:14089
TS27: Bowman's capsule of maturing renal corpuscle Absent GUDMAP:14089
TS27: juxtaglomerular arteriole Absent GUDMAP:14089
TS27: glomerular capillary system Absent GUDMAP:14089
TS27: glomerular mesangium of glomerular tuft Absent GUDMAP:14089
TS27: Bowman's capsule of mature renal corpuscle Absent GUDMAP:14089
TS27: afferent arteriole of mature renal corpuscle Absent GUDMAP:14089
TS27: efferent arteriole of mature renal corpuscle Absent GUDMAP:14089
TS27: extraglomerular mesangium Absent GUDMAP:14089
TS27: cortical renal tubule Absent GUDMAP:14089
TS27: cortical collecting duct Absent GUDMAP:14089
TS27: renal cortical vasculature Absent GUDMAP:14089
TS27: renal medullary interstitium Ambiguous GUDMAP:14089
TS27: renal medullary vasculature Absent GUDMAP:14089
TS27: loop of Henle, outer medullary portion Absent GUDMAP:14089
TS27: outer medullary collecting duct Absent GUDMAP:14089
TS27: loop of Henle, inner medullary portion Absent GUDMAP:14089
TS27: inner medullary collecting duct Absent GUDMAP:14089
TS27: renal pelvis Absent GUDMAP:14089
TS27: outer renal medulla Ambiguous GUDMAP:14089
TS27: outer medullary interstitium Ambiguous GUDMAP:14089
TS27: inner renal medulla Ambiguous GUDMAP:14089
TS27: inner medullary interstitium Ambiguous GUDMAP:14089

Specimen GUDMAP:14090: postnatal day 2 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS27: urinary system Present GUDMAP:14090
TS27: metanephros Present GUDMAP:14090
TS27: nephrogenic zone Present GUDMAP:14090
TS27: nephrogenic interstitium Present GUDMAP:14090
TS27: cap mesenchyme Present GUDMAP:14090
TS27: renal cortex Present GUDMAP:14090
TS27: renal medulla Absent GUDMAP:14090
TS27: renal vesicle Present GUDMAP:14090
TS27: comma-shaped body Present GUDMAP:14090
TS27: s-shaped body Present GUDMAP:14090
TS27: capillary loop renal corpuscle Present GUDMAP:14090
TS27: maturing renal corpuscle Present GUDMAP:14090
TS27: mature renal corpuscle Present GUDMAP:14090
TS27: parietal epithelium of capillary loop renal corpuscle Present GUDMAP:14090
TS27: visceral epithelium of capillary loop renal corpuscle Present GUDMAP:14090
TS27: maturing glomerular tuft Present GUDMAP:14090
TS27: visceral epithelium of maturing renal corpuscle Present GUDMAP:14090
TS27: glomerular tuft Present GUDMAP:14090
TS27: visceral epithelium of mature renal corpuscle Present GUDMAP:14090
TS27: proximal segment of s-shaped body Present GUDMAP:14090
TS27: visceral epithelium of s-shaped body Present GUDMAP:14090
TS27: parietal epithelium of s-shaped body Present GUDMAP:14090
TS27: renal connecting tubule of s-shaped body Absent GUDMAP:14090
TS27: distal segment of s-shaped body Absent GUDMAP:14090
TS27: medial segment of s-shaped body Absent GUDMAP:14090
TS27: ureteric tree terminal branch excluding tip itself Absent GUDMAP:14090
TS27: ureteric tip Absent GUDMAP:14090
TS27: associated interstitium of capillary loop renal corpuscle Absent GUDMAP:14090
TS27: presumptive endothelium of capillary loop renal corpuscle Absent GUDMAP:14090
TS27: presumptive mesangium of capillary loop renal corpuscle Absent GUDMAP:14090
TS27: glomerular capillary system of maturing glomerular tuft Absent GUDMAP:14090
TS27: glomerular mesangium of maturing glomerular tuft Absent GUDMAP:14090
TS27: Bowman's capsule of maturing renal corpuscle Absent GUDMAP:14090
TS27: juxtaglomerular arteriole Absent GUDMAP:14090
TS27: glomerular capillary system Absent GUDMAP:14090
TS27: glomerular mesangium of glomerular tuft Absent GUDMAP:14090
TS27: Bowman's capsule of mature renal corpuscle Absent GUDMAP:14090
TS27: afferent arteriole of mature renal corpuscle Absent GUDMAP:14090
TS27: efferent arteriole of mature renal corpuscle Absent GUDMAP:14090
TS27: extraglomerular mesangium Absent GUDMAP:14090
TS27: cortical renal tubule Absent GUDMAP:14090
TS27: cortical collecting duct Absent GUDMAP:14090
TS27: renal cortical vasculature Absent GUDMAP:14090
TS27: renal pelvis Absent GUDMAP:14090
TS27: proximal renal vesicle Present GUDMAP:14090
TS27: renal cortical interstitium Absent GUDMAP:14090

Specimen GUDMAP:14091: postnatal day 4 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS27: urinary system Present GUDMAP:14091
TS27: metanephros Present GUDMAP:14091
TS27: renal cortex Present GUDMAP:14091
TS27: renal medulla Absent GUDMAP:14091
TS27: renal vesicle Present GUDMAP:14091
TS27: comma-shaped body Present GUDMAP:14091
TS27: s-shaped body Present GUDMAP:14091
TS27: capillary loop renal corpuscle Present GUDMAP:14091
TS27: maturing renal corpuscle Present GUDMAP:14091
TS27: mature renal corpuscle Present GUDMAP:14091
TS27: parietal epithelium of capillary loop renal corpuscle Present GUDMAP:14091
TS27: visceral epithelium of capillary loop renal corpuscle Present GUDMAP:14091
TS27: maturing glomerular tuft Present GUDMAP:14091
TS27: visceral epithelium of maturing renal corpuscle Present GUDMAP:14091
TS27: glomerular tuft Present GUDMAP:14091
TS27: visceral epithelium of mature renal corpuscle Present GUDMAP:14091
TS27: proximal segment of s-shaped body Present GUDMAP:14091
TS27: visceral epithelium of s-shaped body Present GUDMAP:14091
TS27: parietal epithelium of s-shaped body Present GUDMAP:14091
TS27: renal connecting tubule of s-shaped body Absent GUDMAP:14091
TS27: distal segment of s-shaped body Absent GUDMAP:14091
TS27: medial segment of s-shaped body Absent GUDMAP:14091
TS27: ureteric tree terminal branch excluding tip itself Absent GUDMAP:14091
TS27: ureteric tip Absent GUDMAP:14091
TS27: associated interstitium of capillary loop renal corpuscle Absent GUDMAP:14091
TS27: presumptive endothelium of capillary loop renal corpuscle Absent GUDMAP:14091
TS27: presumptive mesangium of capillary loop renal corpuscle Absent GUDMAP:14091
TS27: glomerular capillary system of maturing glomerular tuft Absent GUDMAP:14091
TS27: glomerular mesangium of maturing glomerular tuft Absent GUDMAP:14091
TS27: Bowman's capsule of maturing renal corpuscle Absent GUDMAP:14091
TS27: juxtaglomerular arteriole Absent GUDMAP:14091
TS27: glomerular capillary system Absent GUDMAP:14091
TS27: glomerular mesangium of glomerular tuft Absent GUDMAP:14091
TS27: Bowman's capsule of mature renal corpuscle Absent GUDMAP:14091
TS27: afferent arteriole of mature renal corpuscle Absent GUDMAP:14091
TS27: efferent arteriole of mature renal corpuscle Absent GUDMAP:14091
TS27: extraglomerular mesangium Absent GUDMAP:14091
TS27: cortical renal tubule Absent GUDMAP:14091
TS27: cortical collecting duct Absent GUDMAP:14091
TS27: renal cortical vasculature Absent GUDMAP:14091
TS27: renal pelvis Absent GUDMAP:14091
TS27: proximal renal vesicle Present GUDMAP:14091
TS27: renal cortical interstitium Absent GUDMAP:14091
TS27: nephrogenic zone Absent GUDMAP:14091 There are no pretubular aggregates or cap mesenchyme present at P4 therefore no expression of Wt1 is detected in the nephrogenic zone at P4.
TS27: nephrogenic interstitium Absent GUDMAP:14091

Specimen GUDMAP:14092: postnatal day 6 (more )
Note: Labeling was visualized using BM purple.
Structure Level Pattern Image Note
TS28: metanephros Present GUDMAP:14092
TS28: nephrogenic zone Absent GUDMAP:14092 There are no pretubular aggregates or cap mesenchyme present at P4 therefore no expression of Wt1 is detected in the nephrogenic zone at P4. Also no S-shaped body or Renal Vesicle were present in these sections at P4.
TS28: renal cortex Present GUDMAP:14092
TS28: mature renal corpuscle Present GUDMAP:14092
TS28: glomerular tuft Present GUDMAP:14092
TS28: visceral epithelium of mature renal corpuscle Present GUDMAP:14092
TS28: glomerular capillary system Absent GUDMAP:14092
TS28: glomerular mesangium of glomerular tuft Absent GUDMAP:14092
TS28: Bowman's capsule of mature renal corpuscle Absent GUDMAP:14092
TS28: afferent arteriole of mature renal corpuscle Absent GUDMAP:14092
TS28: efferent arteriole of mature renal corpuscle Absent GUDMAP:14092
TS28: extraglomerular mesangium Absent GUDMAP:14092
TS28: cortical renal tubule Absent GUDMAP:14092
TS28: cortical collecting duct Absent GUDMAP:14092
TS28: renal cortical interstitium Absent GUDMAP:14092
TS28: renal cortical vasculature Absent GUDMAP:14092
TS28: renal medulla Absent GUDMAP:14092
TS28: renal pelvis Absent GUDMAP:14092
TS28: urinary system Present GUDMAP:14092


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
09/17/2024
MGI 6.24
The Jackson Laboratory