Spp2 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
Assay type:	RNA in situ
MGI Accession ID:	MGI:5541805
Gene symbol:	Spp2
Gene name:	secreted phosphoprotein 2

Probe:	RIKEN clone 0610038O04 subclone
Probe preparation:	Antisense labelled with digoxigenin RNA
Visualized with:	Alkaline phosphatase

Results

GUDMAP:9146 ©

Specimen GUDMAP:9146: postnatal adult (more

)
Note: This animal was sexually mature. Labeling was visualized using BM purple.

Structure	Level	Pattern	Image	Note
TS28: urinary system	Present	Regionally restricted	GUDMAP:9146
TS28: metanephros	Present	Regionally restricted	GUDMAP:9146
TS28: renal cortex	Present	Regionally restricted	GUDMAP:9146
TS28: cortical renal tubule	Present	Regionally restricted	GUDMAP:9146	regional expression in subset of proximal convoluted tubules
TS28: renal proximal tubule	Present	Regionally restricted	GUDMAP:9146	regional expression in subset of proximal convoluted tubules
TS28: renal proximal convoluted tubule	Present	Regionally restricted	GUDMAP:9146	regional expression in subset of proximal convoluted tubules
TS28: mature renal corpuscle	Absent		GUDMAP:9146
TS28: glomerular tuft	Absent		GUDMAP:9146
TS28: glomerular capillary system	Absent		GUDMAP:9146
TS28: glomerular mesangium of glomerular tuft	Absent		GUDMAP:9146
TS28: glomerular basement membrane of mature renal corpuscle	Absent		GUDMAP:9146
TS28: visceral epithelium of mature renal corpuscle	Absent		GUDMAP:9146
TS28: Bowman's capsule of mature renal corpuscle	Absent		GUDMAP:9146
TS28: parietal epithelium of mature renal corpuscle	Absent		GUDMAP:9146
TS28: urinary space of mature renal corpuscle	Absent		GUDMAP:9146
TS28: afferent arteriole of mature renal corpuscle	Absent		GUDMAP:9146
TS28: part of afferent arteriole forming the juxtaglomerular complex	Absent		GUDMAP:9146
TS28: rest of afferent arteriole	Absent		GUDMAP:9146
TS28: efferent arteriole of mature renal corpuscle	Absent		GUDMAP:9146
TS28: extraglomerular mesangium	Absent		GUDMAP:9146
TS28: proximal straight tubule, cortical portion	Absent		GUDMAP:9146
TS28: renal distal tubule	Absent		GUDMAP:9146
TS28: distal straight tubule of renal cortex	Absent		GUDMAP:9146
TS28: macula densa	Absent		GUDMAP:9146
TS28: postmacula segment of distal straight tubule	Absent		GUDMAP:9146
TS28: premacula segment of distal straight tubule of renal cortex	Absent		GUDMAP:9146
TS28: distal convoluted tubule	Absent		GUDMAP:9146
TS28: renal connecting tubule	Absent		GUDMAP:9146
TS28: cortical collecting duct	Absent		GUDMAP:9146
TS28: renal cortical interstitium	Absent		GUDMAP:9146
TS28: renal cortical fibroblasts	Absent		GUDMAP:9146
TS28: peritubular fibroblasts of cortex	Absent		GUDMAP:9146
TS28: periarterial fibroblasts of cortex	Absent		GUDMAP:9146
TS28: resident macrophage of the cortex	Absent		GUDMAP:9146
TS28: rest of renal cortical interstitium	Absent		GUDMAP:9146
TS28: renal cortical lymphatics	Absent		GUDMAP:9146
TS28: renal cortical nerves	Absent		GUDMAP:9146
TS28: renal cortical vasculature	Absent		GUDMAP:9146
TS28: renal cortical arterial system	Absent		GUDMAP:9146
TS28: interlobular artery	Absent		GUDMAP:9146
TS28: arcuate artery	Absent		GUDMAP:9146
TS28: renal cortical venous system	Absent		GUDMAP:9146
TS28: interlobular vein	Absent		GUDMAP:9146
TS28: arcuate vein	Absent		GUDMAP:9146
TS28: renal cortical capillary	Absent		GUDMAP:9146
TS28: renal medulla	Absent		GUDMAP:9146
TS28: outer renal medulla	Absent		GUDMAP:9146
TS28: outer stripe of outer medulla	Absent		GUDMAP:9146
TS28: loop of Henle of outer stripe of outer medulla	Absent		GUDMAP:9146
TS28: proximal straight tubule of outer stripe of outer medulla	Absent		GUDMAP:9146
TS28: distal straight tubule of outer stripe of outer medulla	Absent		GUDMAP:9146
TS28: inner stripe of outer medulla	Absent		GUDMAP:9146
TS28: loop of Henle of inner stripe of outer medulla	Absent		GUDMAP:9146
TS28: thin descending limb of inner stripe of outer medulla	Absent		GUDMAP:9146
TS28: premacula segment of distal straight tubule of inner stripe of inner medulla	Absent		GUDMAP:9146
TS28: outer medullary collecting duct	Absent		GUDMAP:9146
TS28: outer medullary interstitium	Absent		GUDMAP:9146
TS28: outer medullary fibroblast	Absent		GUDMAP:9146
TS28: peritubular fibroblasts of outer medulla	Absent		GUDMAP:9146
TS28: periarterial fibroblasts of outer medulla	Absent		GUDMAP:9146
TS28: resident macrophage of the outer medulla	Absent		GUDMAP:9146
TS28: rest of outer medullary interstitium	Absent		GUDMAP:9146
TS28: inner renal medulla	Absent		GUDMAP:9146
TS28: loop of Henle, inner medullary portion	Absent		GUDMAP:9146
TS28: thin descending limb of inner medulla	Absent		GUDMAP:9146
TS28: bend of loop of Henle inner medullary portion	Absent		GUDMAP:9146
TS28: thin ascending limb of inner medulla	Absent		GUDMAP:9146
TS28: inner medullary collecting duct	Absent		GUDMAP:9146
TS28: inner medullary interstitium	Absent		GUDMAP:9146
TS28: inner medullary fibroblast	Absent		GUDMAP:9146
TS28: peritubular fibroblasts of inner medulla	Absent		GUDMAP:9146
TS28: periarterial fibroblasts of inner medulla	Absent		GUDMAP:9146
TS28: resident macrophage of the inner medulla	Absent		GUDMAP:9146
TS28: renal medullary lymphatics	Absent		GUDMAP:9146
TS28: renal medullary nerves	Absent		GUDMAP:9146
TS28: renal medullary vasculature	Absent		GUDMAP:9146
TS28: renal medullary arterial system	Absent		GUDMAP:9146
TS28: renal medullary venous system	Absent		GUDMAP:9146
TS28: renal medullary capillary	Absent		GUDMAP:9146
TS28: renal pelvis	Absent		GUDMAP:9146
TS28: pelvic urothelial lining	Absent		GUDMAP:9146
TS28: pelvic smooth muscle	Absent		GUDMAP:9146
TS28: perihilar interstitium	Absent		GUDMAP:9146
TS28: perihilar fibroblast	Absent		GUDMAP:9146
TS28: resident macrophage of the perihilar interstitium	Absent		GUDMAP:9146
TS28: rest of perihilar interstitium	Absent		GUDMAP:9146
TS28: segment 1 of proximal tubule	Ambiguous		GUDMAP:9146	expression absent from the first portion of segment 1 but uncertain expression in the remainder of segment 1
TS28: segment 2 of proximal tubule	Ambiguous		GUDMAP:9146	expression in proximal convoluted tubule the identity of which may be include segment 2

GUDMAP:9147 ©

Specimen GUDMAP:9147: embryonic day 15.5 (more

)
Note: Labeling was visualized using BM purple.

Structure	Level	Pattern	Image	Note
TS23: urinary system	Present	Regionally restricted	GUDMAP:9147
TS23: metanephros	Present	Regionally restricted	GUDMAP:9147
TS23: renal cortex	Present	Regionally restricted	GUDMAP:9147
TS23: cortical renal tubule	Present	Regionally restricted	GUDMAP:9147	expression in subset of tubules of maturing nephrons only
TS23: cortical early proximal tubule	Present		GUDMAP:9147	expression detected in the first segment of early proximal tubule at urinary pole of maturing renal corpuscles presumptive segment 1
TS23: maturing nephron	Present	Regionally restricted	GUDMAP:9147
TS23: late tubule	Present	Regionally restricted	GUDMAP:9147
TS23: renal capsule	Absent		GUDMAP:9147
TS23: nephrogenic zone	Absent		GUDMAP:9147
TS23: nephrogenic interstitium	Absent		GUDMAP:9147
TS23: cap mesenchyme	Absent		GUDMAP:9147
TS23: pretubular aggregate	Absent		GUDMAP:9147
TS23: ureteric tip	Absent		GUDMAP:9147
TS23: ureteric tree terminal branch excluding tip itself	Absent		GUDMAP:9147
TS23: renal vesicle	Absent		GUDMAP:9147
TS23: comma-shaped body	Absent		GUDMAP:9147
TS23: upper limb of comma-shaped body	Absent		GUDMAP:9147
TS23: lower limb of comma-shaped body	Absent		GUDMAP:9147
TS23: s-shaped body	Absent		GUDMAP:9147
TS23: renal connecting tubule of s-shaped body	Absent		GUDMAP:9147
TS23: distal segment of s-shaped body	Absent		GUDMAP:9147
TS23: medial segment of s-shaped body	Absent		GUDMAP:9147
TS23: proximal segment of s-shaped body	Absent		GUDMAP:9147
TS23: visceral epithelium of s-shaped body	Absent		GUDMAP:9147
TS23: parietal epithelium of s-shaped body	Absent		GUDMAP:9147
TS23: capillary loop renal corpuscle	Absent		GUDMAP:9147
TS23: visceral epithelium of capillary loop renal corpuscle	Absent		GUDMAP:9147
TS23: parietal epithelium of capillary loop renal corpuscle	Absent		GUDMAP:9147
TS23: presumptive mesangium of capillary loop renal corpuscle	Absent		GUDMAP:9147
TS23: presumptive endothelium of capillary loop renal corpuscle	Absent		GUDMAP:9147
TS23: associated interstitium of capillary loop renal corpuscle	Absent		GUDMAP:9147
TS23: maturing renal corpuscle	Absent		GUDMAP:9147
TS23: maturing glomerular tuft	Absent		GUDMAP:9147
TS23: glomerular capillary system of maturing glomerular tuft	Absent		GUDMAP:9147
TS23: glomerular basement membrane of maturing renal corpuscle	Absent		GUDMAP:9147
TS23: glomerular mesangium of maturing glomerular tuft	Absent		GUDMAP:9147
TS23: visceral epithelium of maturing renal corpuscle	Absent		GUDMAP:9147
TS23: Bowman's capsule of maturing renal corpuscle	Absent		GUDMAP:9147
TS23: parietal epithelium of maturing renal corpuscle	Absent		GUDMAP:9147
TS23: glomerular mesangium of maturing renal corpuscle	Absent		GUDMAP:9147
TS23: juxtaglomerular arteriole	Absent		GUDMAP:9147
TS23: renal medullary interstitium	Absent		GUDMAP:9147
TS23: renal medullary vasculature	Absent		GUDMAP:9147
TS23: renal medullary arterial system	Absent		GUDMAP:9147
TS23: renal medullary venous system	Absent		GUDMAP:9147
TS23: renal medullary capillary	Absent		GUDMAP:9147
TS23: medullary collecting duct	Absent		GUDMAP:9147
TS23: renal calyx	Absent		GUDMAP:9147
TS23: renal pelvis	Absent		GUDMAP:9147
TS23: pelvic urothelial lining	Absent		GUDMAP:9147
TS23: pelvic smooth muscle	Absent		GUDMAP:9147
TS23: perihilar interstitium	Absent		GUDMAP:9147
TS23: anlage of loop of Henle of cortical renal tubule	Absent		GUDMAP:9147
TS23: renal connecting tubule	Absent		GUDMAP:9147
TS23: cortical collecting duct	Absent		GUDMAP:9147
TS23: renal cortical interstitium	Absent		GUDMAP:9147
TS23: renal cortical vasculature	Absent		GUDMAP:9147
TS23: renal cortical arterial system	Absent		GUDMAP:9147
TS23: renal cortical venous system	Absent		GUDMAP:9147
TS23: renal cortical capillary	Absent		GUDMAP:9147
TS23: developing capillary loop stage nephron group	Absent		GUDMAP:9147
TS23: collecting duct	Absent		GUDMAP:9147
TS23: renal interstitium	Absent		GUDMAP:9147
TS23: renal vasculature	Absent		GUDMAP:9147
TS23: early nephron	Absent		GUDMAP:9147
TS23: renal medulla	Absent		GUDMAP:9147
TS23: immature loop of Henle	Absent		GUDMAP:9147
TS23: cortical early distal tubule	Ambiguous		GUDMAP:9147	uncertain due to inability to identify tubule subtype
TS23: cortical renal tubule of maturing nephron group	Present	Regionally restricted	GUDMAP:9147
TS23: early proximal tubule of maturing nephron	Present		GUDMAP:9147	expression detected in the first segment of early proximal tubule at urinary pole of maturing renal corpuscles presumptive segment 1
TS23: cortical renal tubule of capillary loop nephron group	Absent		GUDMAP:9147
TS23: early proximal tubule of capillary loop nephron	Absent		GUDMAP:9147
TS23: early distal tubule of capillary loop nephron	Absent		GUDMAP:9147
TS23: renal connecting tubule of capillary loop nephron	Absent		GUDMAP:9147
TS23: renal connecting tubule of maturing nephron	Absent		GUDMAP:9147
TS23: early distal tubule of maturing nephron	Ambiguous		GUDMAP:9147	uncertain due to inability to identify tubule subtype

GUDMAP:9148 ©

Specimen GUDMAP:9148: embryonic day 15.5 (more

)
Note: Labeling was visualized using BM purple.

Structure	Level	Image
TS23: ureter	Absent	GUDMAP:9148
TS23: urothelium of ureter	Absent	GUDMAP:9148
TS23: superficial cell layer of ureter	Absent	GUDMAP:9148
TS23: intermediate cell layer of ureter	Absent	GUDMAP:9148
TS23: basal cell layer of ureter	Absent	GUDMAP:9148
TS23: ureteral mesenchyme	Absent	GUDMAP:9148
TS23: ureteral mesenchyme subepithelial layer	Absent	GUDMAP:9148
TS23: ureteral smooth muscle layer	Absent	GUDMAP:9148
TS23: ureteral smooth muscle layer smooth muscle component	Absent	GUDMAP:9148
TS23: ureteral smooth muscle layer interstitium	Absent	GUDMAP:9148
TS23: ureteral mesenchyme outer layer	Absent	GUDMAP:9148
TS23: ureteral vasculature	Absent	GUDMAP:9148

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24