Wnt2tm2.1(cre/ERT2)Eem
Targeted Allele Detail
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| Symbol: |
Wnt2tm2.1(cre/ERT2)Eem |
| Name: |
wingless-type MMTV integration site family, member 2; targeted mutation 2.1, Edward E Morrisey |
| MGI ID: |
MGI:5544574 |
| Synonyms: |
Wnt2creERT2 |
| Gene: |
Wnt2 Location: Chr6:17988939-18030584 bp, - strand Genetic Position: Chr6, 8.08 cM, cytoband A2-A3.1
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| Alliance: |
Wnt2tm2.1(cre/ERT2)Eem page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:204743
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Targeted (Inducible, Recombinase) |
| Inducer: |
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tamoxifen |
| Mutations: |
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Insertion, Intragenic deletion
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Wnt2tm2.1(cre/ERT2)Eem expression driven by
1 gene
Knock-in expression driven by:
| Organism |
Driver Gene |
Note |
| mouse |
Wnt2 (MGI:98954) |
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Mutation details: A targeting construct was designed so that homologous recombination in ES cells inserted the cre/ERT2 fusion sequence and a neo selection marker after the ATG start codon in exon 1 (replacing exon 1). After establishing germline transmission, Flp-mediated excision removed the neo cassette.
(J:204743)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Wnt2
(mouse)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Wnt2 Mutation: |
26 strains or lines available
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| Original: |
J:204743 Peng T, et al., Coordination of heart and lung co-development by a multipotent cardiopulmonary progenitor. Nature. 2013 Aug 29;500(7464):589-92 |
| All: |
2 reference(s) |
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Analysis Tools
