Slc34a1<tm1(EGFP/cre/ERT2)Bhum> Targeted Allele Detail MGI Mouse (MGI:5544917)

Slc34a1^{tm1(EGFP/cre/ERT2)Bhum}
Targeted Allele Detail

Summary

Symbol:	Slc34a1^{tm1(EGFP/cre/ERT2)Bhum}
Name:	solute carrier family 34 (sodium phosphate), member 1; targeted mutation 1, Benjamin Humphreys
MGI ID:	MGI:5544917
Synonyms:	SLC34a1^GCE
Gene:	Slc34a1 Location: Chr13:55547435-55562508 bp, + strand Genetic Position: Chr13, 29.81 cM, cytoband B
Alliance:	Slc34a1^{tm1(EGFP/cre/ERT2)Bhum} page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:205052
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	(C57BL/6J x 129/Sv)F1

Mutation
description

Allele Type:

Targeted (Inducible, Recombinase, Reporter)

Inducer:

tamoxifen

Mutation:

Insertion

Slc34a1^{tm1(EGFP/cre/ERT2)Bhum} expression driven by 1 gene

Mutation details: An eGFP/cre/ERT2 (GCE) fusion gene with an Frt-flanked neo-polyA cassette were inserted into the ATG translation initiation codon in exon 2 of the Slc34a1 locus by homologous recombination in ES cells. (J:205052)

Generation of Slc34a1^{tm1(EGFP/cre/ERT2)Bhum}

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	Slc34a1 (mouse) Summary of all recombinase alleles driven by Slc34a1. Alliance mouse Slc34a1 gene page

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any Slc34a1 Mutation:	40 strains or lines available

References

Original:	J:205052 Kusaba T, et al., Differentiated kidney epithelial cells repair injured proximal tubule. Proc Natl Acad Sci U S A. 2014 Jan 28;111(4):1527-32
All:	19 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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