Summary | Mutation origin | Mutation description | Recombinase activity | Phenotypes | Disease models | Find Mice (IMSR) | Notes | References

Symbol:	Gt(ROSA)26Sortm3.1(cre/ERT2)Vlcg
Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 3.1, Velocigene
MGI ID:	MGI:5545927
Synonyms:	Gt(ROSA)26SorCreERt2
Gene:	Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance:	Gt(ROSA)26Sortm3.1(cre/ERT2)Vlcg page

Germline Transmission:	Earliest citation of germline transmission: J:200671
Parent Cell Line:	F1H4 (ES Cell)
Strain of Origin:	(129S6/SvEvTac x C57BL/6NTac)F1

Allele Type:    Targeted (Inducible, Recombinase) Inducer:    tamoxifen Mutation:    Insertion   Gt(ROSA)26Sortm3.1(cre/ERT2)Vlcg expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Gt(ROSA)26Sor (MGI:104735)   Mutation details: The targeted construct introcuded into the locus a fusion between phage cre and a modified estrogen receptor (ERT2) and an FRT-flanked hygromycin resistance cassette. Flp-mediated recombination removed the hygromycin resistance cassette. (J:200671)

Activity:	Tissue activity of this recombinase allele
Driver:	Gt(ROSA)26Sor (mouse) Summary of all recombinase alleles driven by Gt(ROSA)26Sor. Alliance mouse Gt(ROSA)26Sor gene page

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:	993 strains or lines available

Original:	J:200671 Economides AN, et al., Conditionals by inversion provide a universal method for the generation of conditional alleles. Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):E3179-88
All:	6 reference(s)