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Gt(ROSA)26Sortm4(flpe)Vlcg
Targeted Allele Detail
Summary
Symbol: Gt(ROSA)26Sortm4(flpe)Vlcg
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 4, Velocigene
MGI ID: MGI:5546037
Synonyms: Gt(ROSA26)SorFLPe
Gene: Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Alliance: Gt(ROSA)26Sortm4(flpe)Vlcg page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:200671
Parent Cell Line:  F1H4 (ES Cell)
Strain of Origin:  (129S6/SvEvTac x C57BL/6NTac)F1
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Gt(ROSA)26Sortm4(flpe)Vlcg expression driven by 1 gene
 
Mutation details: The targeting vector inserted into intron 1 the flpe gene and FRT-flanked drug selection cassette. The insertion produces a 2 bp deletion to accommodate loss of allele genotyping. (J:200671)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Gt(ROSA)26Sor (mouse)
Summary of all recombinase alleles driven by Gt(ROSA)26Sor.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  993 strains or lines available
References
Original:  J:200671 Economides AN, et al., Conditionals by inversion provide a universal method for the generation of conditional alleles. Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):E3179-88
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory