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Dnaaf4tm1.1Jjlo
Targeted Allele Detail
Summary
Symbol: Dnaaf4tm1.1Jjlo
Name: dynein axonemal assembly factor 4; targeted mutation 1.1, Joseph J LoTurco
MGI ID: MGI:5547587
Synonyms: Dyx1c1flox2-4
Gene: Dnaaf4  Location: Chr9:72866067-72880346 bp, + strand  Genetic Position: Chr9, 40.08 cM, cytoband D
Alliance: Dnaaf4tm1.1Jjlo page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:205312
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 2. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 4. Flp-mediated recombination removed the neomycin resistance cassette and left exons 2 through 4 floxed. (J:205312)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dnaaf4 Mutation:  21 strains or lines available
References
Original:  J:205312 Tarkar A, et al., DYX1C1 is required for axonemal dynein assembly and ciliary motility. Nat Genet. 2013 Sep;45(9):995-1003
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory