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Foxl2tm1.1(cre/ERT2)Kliu
Targeted Allele Detail
Summary
Symbol: Foxl2tm1.1(cre/ERT2)Kliu
Name: forkhead box L2; targeted mutation 1.1, Kui Liu
MGI ID: MGI:5548141
Synonyms: Foxl2-CreERT2
Gene: Foxl2  Location: Chr9:98837495-98840601 bp, + strand  Genetic Position: Chr9, 51.41 cM, cytoband E4
Alliance: Foxl2tm1.1(cre/ERT2)Kliu page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:206011
Parent Cell Line:  iTL BA1 (ES Cell)
Strain of Origin:  (C57BL/6NTac x 129S6/SvEvTac)F1
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Foxl2tm1.1(cre/ERT2)Kliu expression driven by 1 gene
 
Mutation details: Homologous recombination was employed to insert an IRES-cre/ERT2-Frt-neo-Frt cassette 259 bp downstream of the stop codon of the Foxl2 gene. Chimeras were bred to C57BL/6 mice, and F1 animals were crossed to flp-expressing mice to delete the neo marker. (J:206011)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Foxl2 (mouse)
Summary of all recombinase alleles driven by Foxl2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Foxl2 Mutation:  15 strains or lines available
References
Original:  J:206011 Zheng W, et al., Two classes of ovarian primordial follicles exhibit distinct developmental dynamics and physiological functions. Hum Mol Genet. 2014 Feb 15;23(4):920-8
All:  6 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory