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Sox3tm2Rlb
Targeted Allele Detail
Summary
Symbol: Sox3tm2Rlb
Name: SRY (sex determining region Y)-box 3; targeted mutation 2, Robin Lovell-Badge
MGI ID: MGI:5550577
Synonyms: floxed Sox3, Sox3flox.gfp
Gene: Sox3  Location: ChrX:59934972-59937036 bp, - strand  Genetic Position: ChrX, 33.66 cM, cytoband A7.3-B
Alliance: Sox3tm2Rlb page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:88507
Parent Cell Line:  AB1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt1+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation details: The endogenous coding region was replaced with a construct containing floxed Sox3 sequence followed by GFP and frt-flanked neo. (J:88507)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sox3 Mutation:  7 strains or lines available
References
Original:  J:88507 Rizzoti K, et al., SOX3 is required during the formation of the hypothalamo-pituitary axis. Nat Genet. 2004 Mar;36(3):247-55
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory