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Gene Expression Data
Assay Details
Assay
Reference: J:116643 Lincoln J, et al., ColVa1 and ColXIa1 are required for myocardial morphogenesis and heart valve development. Dev Dyn. 2006 Dec;235(12):3295-305
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5551424
Gene symbol: Col3a1
Gene name: collagen, type III, alpha 1
Antibody: Collagen III antibody
Detection system: Secondary antibody coupled to Alexa Fluor 488
Assay notes: The authors did not detail the specificity of the antibody, both Col1a1 and Col1a2 have been annotated.
Results
Specimen 6A: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: mitral valve leaflet Weak 6A
Specimen 6B: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: cardiac muscle tissue Weak 6B
Specimen 6C: embryonic day 18.5; Col5a1tm1Rjw/Col5a1+ (more )
Structure Level Pattern Image Note
TS26: mitral valve leaflet Strong 6C There is a 13-fold increased immunoreactivity in this mutant.
Specimen 6D: embryonic day 18.5; Col5a1tm1Rjw/Col5a1+ (more )
Structure Level Pattern Image Note
TS26: cardiac muscle tissue Strong 6D There is a 4-fold increased immunoreactivity in this mutant.
Specimen 6E: embryonic day 18.5; Col11a1cho/Col11a1cho (more )
Structure Level Pattern Image Note
TS26: mitral valve leaflet Strong 6E
Specimen 6F: embryonic day 18.5; Col11a1cho/Col11a1cho (more )
Structure Level Pattern Image Note
TS26: cardiac muscle tissue Weak 6F Expression in this mutant is the same as in wild-type.
Specimen 6G: embryonic day 18.5; Col11a1cho/Col11a1cho, Col5a1tm1Rjw/Col5a1+ (more )
Structure Level Pattern Image Note
TS26: mitral valve leaflet Strong 6G
Specimen 6H: embryonic day 18.5; Col11a1cho/Col11a1cho, Col5a1tm1Rjw/Col5a1+ (more )
Structure Level Pattern Image Note
TS26: cardiac muscle tissue Weak 6H Expression in this mutant is the same as in wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory