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Tg(Gck-cre)#Rck
Transgene Detail
Summary
Symbol: Tg(Gck-cre)#Rck
Name: transgene insertion #, Jeffrey M Friedman
MGI ID: MGI:5551794
Synonyms: Gck-cre
Transgene: Tg(Gck-cre)#Rck  Location: unknown  
Alliance: Tg(Gck-cre)#Rck page
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Gck-cre)#Rck expression driven by 1 gene
 
Mutation details: A BAC (RP23-340E18) containing the Gck locus was modified by inserting cre recombinase with a nuclear localization sequence and a polyA at the ATG site in exon 1 of Gck by homologous recombination in bacterial cells. The purified construct was injected into C57BL/6 pronuclei to generate founders. Line numbers are not available. (J:206002)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Gck (mouse)
Summary of all recombinase alleles driven by Gck.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:206002 Stanley S, et al., Profiling of Glucose-Sensing Neurons Reveals that GHRH Neurons Are Activated by Hypoglycemia. Cell Metab. 2013 Oct 1;18(4):596-607
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
08/02/2024
MGI 6.24 		The Jackson Laboratory