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Tg(Slc6a3-icre)9190Gsc
Transgene Detail
Summary
Symbol: Tg(Slc6a3-icre)9190Gsc
Name: transgene insertion 9190, Gunther Schutz
MGI ID: MGI:5554573
Synonyms: DATCre
Transgene: Tg(Slc6a3-icre)9190Gsc  Location: unknown  
Alliance: Tg(Slc6a3-icre)9190Gsc page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Slc6a3-icre)9190Gsc expression driven by 1 gene
 
Mutation detailsThe improved codon cre open reading frame was inserted at the translation initiation site of Slc6a3 to create a transgene that drives expression of cre in the brain. Lines 9075 (2 copies of the transgene), 9190 (3 copies) and 9140 (5 copies) were generated. (J:114551)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Slc6a3 (species not specified)
Summary of all recombinase alleles driven by Slc6a3.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:114551 Parlato R, et al., Survival of DA neurons is independent of CREM upregulation in absence of CREB. Genesis. 2006 Oct;44(10):454-64
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory