Tg(hs23-Ccre,-lacZ)1Fawa
Transgene Detail
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| Symbol: |
Tg(hs23-Ccre,-lacZ)1Fawa |
| Name: |
transgene insertion 1, Fan Wang |
| MGI ID: |
MGI:5556209 |
| Synonyms: |
CreC23 |
| Transgene: |
Tg(hs23-Ccre,-lacZ)1Fawa Location: unknown
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| Alliance: |
Tg(hs23-Ccre,-lacZ)1Fawa page
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| Strain of Origin: |
Not Specified
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| Transgene Type: |
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Transgenic (Recombinase) |
| Mutation: |
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Insertion
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Tg(hs23-Ccre,-lacZ)1Fawa expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| human |
hs23 |
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Mutation details: The C-terminal fragment of cre recombinase (aa 60-343) fused to the intein-C peptide fragment (36 C terminal amino acids) of the DnaE split intein sequence was cloned into a vector containing the human enhancer 23 sequence (hs23) and an Hsp68 minimal promoter and lacZ reporter. The final construct included an IRES sequence separating the lacZ gene and Ccre-intein-C. Injection of the linearized construct into pronuclei was performed to generated transgenic founders. Line numbers were not identified in the publication.
(J:207270)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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hs23
(human)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Examples of reporter expression driven by this and other human enhancers in mouse embryos produced by transient transgenesis can be viewed at http://enhancer.lbl.gov.
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| Original: |
J:207270 Wang P, et al., Intersectional Cre driver lines generated using split-intein mediated split-Cre reconstitution. Sci Rep. 2012;2:497 |
| All: |
1 reference(s) |
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Analysis Tools
