Tg(Hcn4-cre/ERT2)1Yzhao
Transgene Detail
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| Symbol: |
Tg(Hcn4-cre/ERT2)1Yzhao |
| Name: |
transgene insertion 1, Yong Zhao |
| MGI ID: |
MGI:5562295 |
| Synonyms: |
Hcn4-CreERT2 |
| Transgene: |
Tg(Hcn4-cre/ERT2)1Yzhao Location: unknown
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| Alliance: |
Tg(Hcn4-cre/ERT2)1Yzhao page
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| Strain of Origin: |
Not Specified
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| Transgene Type: |
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Transgenic (Inducible, Recombinase) |
| Inducer: |
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tamoxifen |
| Mutation: |
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Insertion
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Tg(Hcn4-cre/ERT2)1Yzhao expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| Not Specified |
Hcn4 |
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Mutation details: Recombineering methods were used to insert a cre/ERT2 cassette immediately after the ATG start codon of the Hcn4 locus in a bacterial artificial chromosome (this BAC does not encode other proteins or micro RNAs). The BAC construct was purified and used for pronuclear injection of fertilized oocytes. Two founders were generated, with essentially identical cre activity patterns following tamoxifen treatment being observed. One line was chosen for detailed analyses.
(J:207828)
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Generation of Tg(Hcn4-cre/ERT2)1Yzhao. |
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Hcn4
(species not specified)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:207828 Wu M, et al., Inducible gene deletion in the entire cardiac conduction system using Hcn4-CreERT2 BAC transgenic mice. Genesis. 2014 Feb;52(2):134-40 |
| All: |
3 reference(s) |
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Analysis Tools
