Tg(Hdc-cre)#Jmz
Transgene Detail
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| Symbol: |
Tg(Hdc-cre)#Jmz |
| Name: |
transgene insertion, Jeffrey M Zigman |
| MGI ID: |
MGI:5562453 |
| Synonyms: |
HDC-Cre` |
| Transgene: |
Tg(Hdc-cre)#Jmz Location: unknown
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| Alliance: |
Tg(Hdc-cre)#Jmz page
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| Transgene Type: |
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Transgenic (Recombinase) |
| Mutation: |
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Insertion
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Tg(Hdc-cre)#Jmz expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| mouse |
Hdc (MGI:96062) |
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Mutation details: A BAC (RP24-14N14) containing the entire histidine decarboxylase (Hdc) gene was modified in bacterial cells, replacing the first 47 amino acids of exon 2, intron 1, and exon 1 of Hdc with the cre recombinase coding sequence, SV40 polyadenylation signal and Frt-flanked kanamycin marker. Flp recombination removed the kanamycin cassette. Pronuclear injection of the verified construct produced founder mice. Multiple founders were generated. One founder was verified to have the transgene and produce the expected cre activity in the CNS.
(J:194386)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Hdc
(mouse)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:194386 Yanovsky Y, et al., Proton- and ammonium-sensing by histaminergic neurons controlling wakefulness. Front Syst Neurosci. 2012;6:23 |
| All: |
5 reference(s) |
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Analysis Tools
