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Ikzf1tm2.1Smale
Targeted Allele Detail
Summary
Symbol: Ikzf1tm2.1Smale
Name: IKAROS family zinc finger 1; targeted mutation 2.1, Stephen T Smale
MGI ID: MGI:5563076
Synonyms: Ikzf1deltaF4
Gene: Ikzf1  Location: Chr11:11634980-11722926 bp, + strand  Genetic Position: Chr11, 7.02 cM
Alliance: Ikzf1tm2.1Smale page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:208211
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Not Applicable)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: Cre-mediated recombination removed exon 6, which encodes zinc finger 4, and a neomycin resistance cassette. (J:208211)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 3 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 6 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ikzf1 Mutation:  30 strains or lines available
References
Original:  J:208211 Schjerven H, et al., Selective regulation of lymphopoiesis and leukemogenesis by individual zinc fingers of Ikaros. Nat Immunol. 2013 Oct;14(10):1073-83
All:  4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory