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Shox2tm1.1(cre)Oki
Targeted Allele Detail
Summary
Symbol: Shox2tm1.1(cre)Oki
Name: SHOX homeobox 2; targeted mutation 1.1, Ole Kiehn
MGI ID: MGI:5567920
Synonyms: Shox2::Cre
Gene: Shox2  Location: Chr3:66879060-66889104 bp, - strand  Genetic Position: Chr3, 30.76 cM, cytoband E3-F1
Alliance: Shox2tm1.1(cre)Oki page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:209344
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEv
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Shox2tm1.1(cre)Oki expression driven by 1 gene
 
Mutation details: Homologous recombination in ES cells inserted an IRES-nlscre and frt-flanked PGK-neo cassette after the stop codon of the Shox2 coding sequence. The neo was removed by crossing to FLPeR deleter animals. (J:209344)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Shox2 (mouse)
Summary of all recombinase alleles driven by Shox2.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Shox2 Mutation:  20 strains or lines available
References
Original:  J:209344 Dougherty KJ, et al., Locomotor rhythm generation linked to the output of spinal shox2 excitatory interneurons. Neuron. 2013 Nov 20;80(4):920-33
All:  8 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory