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Gad2tm1(cre)Bvz
Targeted Allele Detail
Summary
Symbol: Gad2tm1(cre)Bvz
Name: glutamic acid decarboxylase 2; targeted mutation 1, Boris V Zemelman
MGI ID: MGI:5568691
Synonyms: Gad65-cre
Gene: Gad2  Location: Chr2:22512262-22583889 bp, + strand  Genetic Position: Chr2, 15.15 cM, cytoband A-B
Alliance: Gad2tm1(cre)Bvz page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:209715
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  C57BL/6 x 129/Sv
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Gad2tm1(cre)Bvz expression driven by 1 gene
 
Mutation details: The cre recombinase coding sequence following an internal ribosome entry site (IRES-cre) was inserted into the 3' UTR of the Gad2 (Gad65) gene by homologous recombination in ES cells. (J:209715)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Gad2 (mouse)
Summary of all recombinase alleles driven by Gad2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gad2 Mutation:  60 strains or lines available
Notes
ES cells = C57BL/6-129/SV hybrid cells.
References
Original:  J:209715 Lovett-Barron M, et al., Regulation of neuronal input transformations by tunable dendritic inhibition. Nat Neurosci. 2012 Mar;15(3):423-30, S1-3
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/19/2024
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