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Ssttm1(cre)Bvz
Targeted Allele Detail
Summary
Symbol: Ssttm1(cre)Bvz
Name: somatostatin; targeted mutation 1, Boris V Zemelman
MGI ID: MGI:5568693
Synonyms: Som-cre, Som-IRES-Cre, SST-IRES-Cre
Gene: Sst  Location: Chr16:23708323-23709708 bp, - strand  Genetic Position: Chr16, 15.0 cM, cytoband cen-C3
Alliance: Ssttm1(cre)Bvz page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:209715
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  C57BL/6 x 129/Sv
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Ssttm1(cre)Bvz expression driven by 1 gene
 
Mutation detailsThe cre recombinase coding sequence following an internal ribosome entry site (IRES-cre) was inserted into the 3' UTR of the somatostatin (Sst) gene by homologous recombination in ES cells. (J:209715)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Sst (mouse)
Summary of all recombinase alleles driven by Sst.
 

Expression
In Mice Carrying this Mutation: 9 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sst Mutation:  35 strains or lines available
References
Original:  J:209715 Lovett-Barron M, et al., Regulation of neuronal input transformations by tunable dendritic inhibition. Nat Neurosci. 2012 Mar;15(3):423-30, S1-3
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
07/02/2024
MGI 6.13
The Jackson Laboratory