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Tg(Pomc-cre/ERT2)#Jke
Transgene Detail
Summary
Symbol: Tg(Pomc-cre/ERT2)#Jke
Name: transgene insertion, Joel K Elmquist
MGI ID: MGI:5569339
Synonyms: POMC-cre:ERT2
Transgene: Tg(Pomc-cre/ERT2)#Jke  Location: unknown  
Alliance: Tg(Pomc-cre/ERT2)#Jke page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Pomc-cre/ERT2)#Jke expression driven by 1 gene
 
Mutation detailsA cre/ERT2 fusion sequence was put under the control of Pomc regulatory elements in a transgenic construct. Microinjection of the construct resulted in the generation of founder lines which were screened by crosses to reporter mice and treating progeny with tamoxifen to induce cre recombination. (J:207704)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Pomc (species not specified)
Summary of all recombinase alleles driven by Pomc.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:207704 Berglund ED, et al., Serotonin 2C receptors in pro-opiomelanocortin neurons regulate energy and glucose homeostasis. J Clin Invest. 2013 Dec 2;123(12):5061-70
All:  28 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory