Tg(Ltf-icre)14Mmul
Transgene Detail
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| Symbol: |
Tg(Ltf-icre)14Mmul |
| Name: |
transgene insertion 14, Mathias Muller |
| MGI ID: |
MGI:5571915 |
| Synonyms: |
Ltf-Cre |
| Transgene: |
Tg(Ltf-icre)14Mmul Location: unknown
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| Alliance: |
Tg(Ltf-icre)14Mmul page
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| Transgene Type: |
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Transgenic (Recombinase) |
| Mutation: |
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Insertion
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Tg(Ltf-icre)14Mmul expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| Not Specified |
Ltf |
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Mutation details: A BAC (RP24-166N8) containing the Ltf gene was modified in bacterial cells to produce the targeting construct. A cassette containing codon-improved cre recombinase (icre), an artificial intron, the bovine growth hormone polyadenylation signal and an frt-flanked ampicillin selection marker was inserted into the first exon of Ltf. A plasmid endoding Flp was transfected into E. coli cells to delete the amp-marker. The BAC construct was verified by sequencing and microinjected into pronuclei of (B6/129Sv)F1 oocytes to produce transgenic animals. 2 lines (14 and 15) were obtained. Line 14 was chosen for further analysis.
(J:210800)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Ltf
(species not specified)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 2 strains available
Cell Lines: 0 lines available
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| Original: |
J:210800 Kovacic B, et al., Lactotransferrin-Cre reporter mice trace neutrophils, monocytes/macrophages and distinct subtypes of dendritic cells. Haematologica. 2014 Jun;99(6):1006-15 |
| All: |
4 reference(s) |
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Analysis Tools
