Tg(Cma1-cre)#Roer
Transgene Detail
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Symbol: |
Tg(Cma1-cre)#Roer |
Name: |
transgene insertion, Axel Roers |
MGI ID: |
MGI:5572820 |
Synonyms: |
Mcpt5-Cre |
Transgene: |
Tg(Cma1-cre)#Roer Location: unknown
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Alliance: |
Tg(Cma1-cre)#Roer page
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Transgene Type: |
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Transgenic (Recombinase) |
Mutation: |
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Insertion
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Tg(Cma1-cre)#Roer expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Cma1 (MGI:96941) |
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Mutation details: This transgene contains a modified BAC RP23-284A14 in which a cre and floxed neo cassette was inserted into exon 1 replacing a portion of the coding region. Cre-mediated deletion was used to remove the neo cassette. Six founder lines were generated one with only 80% of peritoneal mast cells expressing the transgene that was not further examined and two other lines expressing in 100% of peritoneal cells in an autosomal inheritance pattern (line A) and the other in an X-linked inheritance pattern (line X). The pound symbol (#) is used when no line is specified and/or lines are pooled.
(J:133910)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Cma1
(mouse)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:209168 Abramova A, et al., The transcription factor MAZR preferentially acts as a transcriptional repressor in mast cells and plays a minor role in the regulation of effector functions in response to FcepsilonRI stimulation. PLoS One. 2013;8(10):e77677 |
All: |
38 reference(s) |
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