Dlx2<tm1.1Rth> Targeted Allele Detail MGI Mouse (MGI:5575409)

Dlx2^tm1.1Rth
Targeted Allele Detail

Summary

Symbol:	Dlx2^tm1.1Rth
Name:	distal-less homeobox 2; targeted mutation 1.1, David H Rowitch
MGI ID:	MGI:5575409
Synonyms:	Dlx1/Dlx2^tm1.1Rth
Gene:	Dlx2 Location: Chr2:71373752-71377095 bp, - strand Genetic Position: Chr2, 42.65 cM
Alliance:	Dlx2^tm1.1Rth page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:212992
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	(C57BL/6 x 129S/SvEv)F1

Mutation
description

Allele Type:		Targeted (Conditional ready)
Mutation:		Insertion
		Mutation details: An FRT-flanked PGK-neomycin cassette and loxP site were placed in intron 1. Flp-mediated recombination removed the selection cassette. (J:212992)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any Dlx2 Mutation:	25 strains or lines available

Notes

This allele was generated in ES cells in conjunction with Dlx1^tm1Rth.

References

Original:	J:212992 Silbereis JC, et al., Olig1 function is required to repress dlx1/2 and interneuron production in Mammalian brain. Neuron. 2014 Feb 5;81(3):574-87
All:	5 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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