About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:124197 Kiyozumi D, et al., Frem3, a member of the 12 CSPG repeats-containing extracellular matrix protein family, is a basement membrane protein with tissue distribution patterns distinct from those of Fras1, Frem2, and QBRICK/Frem1. Matrix Biol. 2007 Jul;26(6):456-462
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5578519
Gene symbol: Lamc1
Gene name: laminin, gamma 1
Antibody: mAb 1914
Detection system: Secondary antibody coupled to rhodamine
Assay notes: Cryosections were fixed in absolute ethanol.
Results
Specimen 2B Frem3: postnatal week 9 (more )
Note: Double labeled: red - Lamc1; green - Frem3 (assay MGI:5578504).
Structure Level Pattern Image Note
TS28: retina layer Present Regionally restricted 2B Frem3 Expression is at the basement membrane.
Specimen 2B Fras1: postnatal week 9 (more )
Note: Double labeled: red - Lamc1; green - Fras1 (assay MGI:5578525).
Structure Level Pattern Image Note
TS28: retina layer Present Regionally restricted 2B Fras1 Expression is at the basement membrane.
Specimen 2B Frem2: postnatal week 9 (more )
Note: Double labeled: red - Lamc1; green - Frem2 (assay MGI:5578613).
Structure Level Pattern Image Note
TS28: retina layer Present Regionally restricted 2B Frem2 Expression is at the basement membrane.
Specimen 2B QBRICK/Frem1: postnatal week 9 (more )
Note: Double labeled: red - Lamc1; green - Frem1 (assay MGI:5578614).
Structure Level Pattern Image Note
TS28: retina layer Present Regionally restricted 2B QBRICK/Frem1 Expression is at the basement membrane.
Specimen 2C Fem3: embryonic day 14.5 (more )
Note: Double labeled: red - Lamc1; green - Frem3 (assay MGI:5578504).
Structure Level Pattern Image Note
TS22: retina Present Regionally restricted 2C Frem3 Expression is at the basement membrane.
Specimen 2C Fras1: embryonic day 14.5 (more )
Note: Double labeled: red - Lamc1; green - Fras1 (assay MGI:5578525).
Structure Level Pattern Image Note
TS22: retina Present Regionally restricted 2C Fras1 Expression is at the basement membrane.
Specimen 2C Frem2: embryonic day 14.5 (more )
Note: Double labeled: red - Lamc1; green - Frem2 (assay MGI:5578613).
Structure Level Pattern Image Note
TS22: retina Present Regionally restricted 2C Frem2 Expression is at the basement membrane.
Specimen 2C QBERICK/Frem1: embryonic day 14.5 (more )
Note: Double labeled: red - Lamc1; green - Frem1 (assay MGI:5578614).
Structure Level Pattern Image Note
TS22: retina Present Regionally restricted 2C QBRICK/Frem1 Expression is at the basement membrane.
Specimen 2D Frem3: postnatal adult; Frem2my/Frem2my (more )
Note: Double labeled: red - Lamc1; green - Frem3 (assay MGI:5578504).
Structure Level Pattern Image Note
TS28: salivary gland Present Regionally restricted 2D Frem3 Expression is at the basement membrane.
Specimen 2D Fras1: postnatal adult (more )
Note: Double labeled: red - Lamc1; green - Fras1 (assay MGI:5578525).
Structure Level Pattern Image Note
TS28: salivary gland Present Regionally restricted 2D Fras1 Expression is at the basement membrane.
Specimen 2D Frem2: postnatal adult (more )
Note: Double labeled: red - Lamc1; green - Frem2 (assay MGI:5578613).
Structure Level Pattern Image Note
TS28: salivary gland Present Regionally restricted 2D Frem2 Expression is at the basement membrane.
Specimen 2D QBRICK/Frem1: postnatal adult (more )
Note: Double labeled: red - Lamc1; green - Frem1 (assay MGI:5578614).
Structure Level Pattern Image Note
TS28: salivary gland Present Regionally restricted 2D QBRICK/Frem1 Expression is at the basement membrane.
Specimen 2E Frem3: embryonic day 14.5 (more )
Note: Double labeled: red - Lamc1; green - Frem3 (assay MGI:5578504).
Structure Level Pattern Image Note
TS22: metanephros Present Regionally restricted 2E Frem3 Expression is at the basement membrane.
Specimen 2E Fras1: embryonic day 14.5 (more )
Note: Double labeled: red - Lamc1; green - Fras1 (assay MGI:5578525).
Structure Level Pattern Image Note
TS22: metanephros Present Regionally restricted 2E Fras1 Expression is at the basement membrane.
Specimen 2E Frem2: embryonic day 14.5 (more )
Note: Double labeled: red - Lamc1; green - Frem2 (assay MGI:5578613).
Structure Level Pattern Image Note
TS22: metanephros Present Regionally restricted 2E Frem2 Expression is at the basement membrane.
Specimen 2E QBRICK/Frem1: embryonic day 14.5 (more )
Note: Double labeled: red - Lamc1; green - Frem1 (assay MGI:5578614).
Structure Level Pattern Image Note
TS22: metanephros Present Regionally restricted 2E QBRICK/Frem1 Expression is at the basement membrane.
Specimen 3A first: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: epidermis Present Regionally restricted 3A bottom first Expression is at the basement membrane.
TS25: hair follicle Present Regionally restricted 3A bottom first Expression is at the basement membrane.
Specimen 3A second: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: epidermis Present Regionally restricted 3A bottom second Expression is at the basement membrane.
TS25: hair follicle Present Regionally restricted 3A bottom second Expression is at the basement membrane.
Specimen 3A third: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: epidermis Present Regionally restricted 3A bottom third Expression is at the basement membrane.
TS25: hair follicle Present Regionally restricted 3A bottom third Expression is at the basement membrane.
Specimen 3A fourth: embryonic day 17.5 (more )
Structure Level Pattern Image Note
TS25: epidermis Present Regionally restricted 3A bottom fourth Expression is at the basement membrane.
TS25: hair follicle Present Regionally restricted 3A bottom fourth Expression is at the basement membrane.
Specimen 3B Frem3: postnatal week 4 (more )
Note: Panels at the right are higher magnifications of the boxed areas. Double labeled: red - Lamc1; green - Frem3 (assay MGI:5578504).
Structure Level Pattern Image Note
TS28: coat hair follicle Present Regionally restricted 3B Frem3 Expression is at the basement membrane.
TS28: epidermis Present Regionally restricted 3B Frem3 Expression is at the basement membrane.
TS28: hair outer root sheath Present Regionally restricted 3B Frem3 Expression is at the basement membrane.
Specimen 3B Fras1: postnatal week 4 (more )
Note: Panels at the right are higher magnifications of the boxed areas. Double labeled: red - Lamc1; green - Fras1 (assay MGI:5578525).
Structure Level Pattern Image Note
TS28: coat hair follicle Present Regionally restricted 3B Fras1 Expression is at the basement membrane.
TS28: epidermis Present Regionally restricted 3B Fras1 Expression is at the basement membrane.
TS28: hair outer root sheath Present Regionally restricted 3B Fras1 Expression is at the basement membrane.
Specimen 3B Frem2: postnatal week 4 (more )
Note: Panels at the right are higher magnifications of the boxed areas. Double labeled: red - Lamc1; green - Frem2 (assay MGI:5578613).
Structure Level Pattern Image Note
TS28: coat hair follicle Present Regionally restricted 3B Frem2 Expression is at the basement membrane.
TS28: epidermis Present Regionally restricted 3B Frem2 Expression is at the basement membrane.
TS28: hair outer root sheath Present Regionally restricted 3B Frem2 Expression is at the basement membrane.
Specimen 3B QBRICK/Frem1: postnatal week 4 (more )
Note: Panels at the right are higher magnifications of the boxed areas. Double labeled: red - Lamc1; green - Frem1 (assay MGI:5578614).
Structure Level Pattern Image Note
TS28: coat hair follicle Present Regionally restricted 3B QBRICK/Frem1 Expression is at the basement membrane.
TS28: epidermis Present Regionally restricted 3B QBRICK/Frem1 Expression is at the basement membrane.
TS28: hair outer root sheath Present Regionally restricted 3B QBRICK/Frem1 Expression is at the basement membrane.
Specimen 4A Qbrick/Frem1+/- first: postnatal newborn; Frem1tm1Ksek/Frem1+ (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Qbrick/Frem1+/- LNg1 first Expression is at the basement membrane.
Specimen 4A Qbrick/Frem1+/- second: postnatal newborn; Frem1tm1Ksek/Frem1+ (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Qbrick/Frem1+/- LNg1 second Expression is at the basement membrane.
Specimen 4A Qbrick/Frem1+/- third: postnatal newborn; Frem1tm1Ksek/Frem1+ (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Qbrick/Frem1+/- LNg1 third Expression is at the basement membrane.
Specimen 4A Qbrick/Frem1+/- fourth: postnatal newborn; Frem1tm1Ksek/Frem1+ (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Qbrick/Frem1+/- LNg1 fourth Expression is at the basement membrane.
Specimen 4A Qbrick/Frem1-/- first: postnatal newborn; Frem1tm1Ksek/Frem1tm1Ksek (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Qbrick/Frem1-/- LNg1 first Expression is at the basement membrane.
Specimen 4A Qbrick/Frem1-/- second: postnatal newborn; Frem1tm1Ksek/Frem1tm1Ksek (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Qbrick/Frem1-/- LNg1 second Expression is at the basement membrane.
Specimen 4A Qbrick/Frem1-/- third: postnatal newborn; Frem1tm1Ksek/Frem1tm1Ksek (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Qbrick/Frem1-/- LNg1 third Expression is at the basement membrane.
Specimen 4A Qbrick/Frem1-/- fourth: postnatal newborn; Frem1tm1Ksek/Frem1tm1Ksek (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Qbrick/Frem1-/- LNg1 fourth Expression is at the basement membrane.
Specimen 4A Frem2my/+ first: postnatal newborn; Frem2my/Frem2+ (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Frem2my/+ LNg1 first Expression is at the basement membrane.
Specimen 4A Frem2my/+ second: postnatal newborn; Frem2my/Frem2+ (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Frem2my/+ LNg1 second Expression is at the basement membrane.
Specimen 4A Frem2my/+ third: postnatal newborn; Frem2my/Frem2+ (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Frem2my/+ LNg1 third Expression is at the basement membrane.
Specimen 4A Frem2my/+ fourth: postnatal newborn; Frem2my/Frem2+ (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Frem2my/+ LNg1 fourth Expression is at the basement membrane.
Specimen 4A Frem2my/my first: postnatal newborn; Frem2my/Frem2my (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Frem2my/my LNg1 first Expression is at the basement membrane.
Specimen 4A Frem2my/my second: postnatal newborn; Frem2my/Frem2my (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Frem2my/my LNg1 second Expression is at the basement membrane.
Specimen 4A Frem2my/my third: postnatal newborn; Frem2my/Frem2my (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Frem2my/my LNg1 third Expression is at the basement membrane.
Specimen 4A Frem2my/my fourth: postnatal newborn; Frem2my/Frem2my (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Frem2my/my LNg1 fourth Expression is at the basement membrane.
Specimen 4A Grip1eb/+ first: postnatal newborn; Grip1eb/Grip1+ (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Grip1eb/+ LNg1 first Expression is at the basement membrane.
Specimen 4A Grip1eb/+ second: postnatal newborn; Grip1eb/Grip1+ (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Grip1eb/+ LNg1 second Expression is at the basement membrane.
Specimen 4A Grip1eb/+ third: postnatal newborn; Grip1eb/Grip1+ (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Grip1eb/+ LNg1 third Expression is at the basement membrane.
Specimen 4A Grip1eb/+ fourth: postnatal newborn; Grip1eb/Grip1+ (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Grip1eb/+ LNg1 fourth Expression is at the basement membrane.
Specimen 4A Grip1eb/eb first: postnatal newborn; Grip1eb/Grip1eb (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Grip1eb/eb LNg1 first Expression is at the basement membrane.
Specimen 4A Grip1eb/eb second: postnatal newborn; Grip1eb/Grip1eb (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Grip1eb/eb LNg1 second Expression is at the basement membrane.
Specimen 4A Grip1eb/eb third: postnatal newborn; Grip1eb/Grip1eb (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Grip1eb/eb LNg1 third Expression is at the basement membrane.
Specimen 4A Grip1eb/eb fourth: postnatal newborn; Grip1eb/Grip1eb (more )
Structure Level Pattern Image Note
TS27: epidermis Present Regionally restricted 4A Grip1eb/eb LNg1 fourth Expression is at the basement membrane.
Specimen 4B Frem2my/+: embryonic day 13.5; Frem2my/Frem2+ (more )
Structure Level Pattern Image Note
TS21: epidermis Present Regionally restricted 4B Frem2my/+ LNg1 Expression is at the basement membrane.
Specimen 4B Frem2my/my: embryonic day 13.5; Frem2my/Frem2my (more )
Structure Level Pattern Image Note
TS21: epidermis Present Regionally restricted 4B Frem2my/my LNg1 Expression is at the basement membrane.
Specimen 4C Grip1eb/+: embryonic day 14.5; Grip1eb/Grip1+ (more )
Structure Level Pattern Image Note
TS22: epidermis Present Regionally restricted 4C Grip1eb/+ LNg1 Expression is at the basement membrane.
Specimen 4C Grip1eb/eb: embryonic day 14.5; Grip1eb/Grip1eb (more )
Structure Level Pattern Image Note
TS22: epidermis Present Regionally restricted 4C Grip1eb/eb LNg1 Expression is at the basement membrane.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/17/2024
MGI 6.24 		The Jackson Laboratory