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Tmprss2tm3Sho
Targeted Allele Detail
Summary
Symbol: Tmprss2tm3Sho
Name: transmembrane protease, serine 2; targeted mutation 3, Stuart Orkin
MGI ID: MGI:5578610
Synonyms: mTmprss2-L-S-L
Gene: Tmprss2  Location: Chr16:97365882-97412395 bp, - strand  Genetic Position: Chr16, 57.53 cM, cytoband C2
Alliance: Tmprss2tm3Sho page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:212219
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Not Applicable)
Mutations:    Insertion, Intragenic deletion
    Exon 2 was replaced with a floxed neomycin resistance cassette, stopper cassette and loxP site. (J:212219)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tmprss2 Mutation:  55 strains or lines available
References
Original:  J:212219 Baena E, et al., ETV1 directs androgen metabolism and confers aggressive prostate cancer in targeted mice and patients. Genes Dev. 2013 Mar 15;27(6):683-98
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory