Brinp1<tm1.1Pib> Targeted Allele Detail MGI Mouse (MGI:5604542)

Brinp1^tm1.1Pib
Targeted Allele Detail

Summary

Symbol:	Brinp1^tm1.1Pib
Name:	bone morphogenic protein/retinoic acid inducible neural specific 1; targeted mutation 1.1, Phillip I Bird
MGI ID:	MGI:5604542
Gene:	Brinp1 Location: Chr4:68679751-68872634 bp, - strand Genetic Position: Chr4, 35.03 cM, cytoband C2
Alliance:	Brinp1^tm1.1Pib page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:231288
Parent Cell Line:	Bruce 4 (ES Cell)
Strain of Origin:	B6.Cg-Thy1^a

Mutation
description

Allele Type:		Targeted (Null/knockout)
Mutations:		Insertion, Intragenic deletion
		Mutation details: This mutation was generated from the conditional allele by cre recombinase excision of exon 3 and a frt sequence-flanked neomycin resistance cassette in intron 3, leaving a single loxP site. (J:231288)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Disease models

Expression

In Structures Affected by this Mutation:

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Brinp1 Mutation:	30 strains or lines available

References

Original:	J:231288 Berkowicz SR, et al., Brinp1 (-/-) mice exhibit autism-like behaviour, altered memory, hyperactivity and increased parvalbumin-positive cortical interneuron density. Mol Autism. 2016;7:22
All:	1 reference(s)

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