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Tg(Arc-cre/ERT2)MRhn
Transgene Detail
Summary
Symbol: Tg(Arc-cre/ERT2)MRhn
Name: transgene insertion M, Rene Hen
MGI ID: MGI:5607252
Synonyms: ArcCreERT2
Transgene: Tg(Arc-cre/ERT2)MRhn  Location: unknown  
Alliance: Tg(Arc-cre/ERT2)MRhn page
Transgene
origin
Strain of Origin:  C57BL/6J x CBA
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tg(Arc-cre/ERT2)MRhn expression driven by 1 gene
 
Mutation detailsBacterial artificial chromosome (BAC) library (CHORI) was used to obtain a BAC (#RP23-429N15) containing the entire mouse activity regulated cytoskeletal-associated protein (Arc) gene. A CreERT2 fusion gene (a Cre recombinase fused to a human estrogen receptor ligand-binding domain), followed by an SV40 polyadenylation sequence, was inserted into the translation initiation site of the gene. Founder lines M and F were established and maintained. (J:215456)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Arc (mouse)
Summary of all recombinase alleles driven by Arc.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:215456 Denny CA, et al., Hippocampal memory traces are differentially modulated by experience, time, and adult neurogenesis. Neuron. 2014 Jul 2;83(1):189-201
All:  13 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory