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Gene Expression Data
Assay Details
Assay
Reference: J:1619 Peters KG, et al., Two FGF receptor genes are differentially expressed in epithelial and mesenchymal tissues during limb formation and organogenesis in the mouse. Development. 1992 Jan;114(1):233-43
Assay type: RNA in situ
MGI Accession ID: MGI:5609967
Gene symbol: Fgfr1
Gene name: fibroblast growth factor receptor 1
Probe: Fgfr1 cDNA2
Probe preparation: Antisense labelled with S35 RNA
Results
Specimen not shown: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: limb mesenchyme Present Diffuse
TS15: dermatome Present
TS15: sclerotome Present
TS15: tracheal diverticulum mesenchyme Present
TS15: myotome Absent

Specimen 2B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: limb mesenchyme Present Diffuse 2B
TS17: future spinal cord Present Regionally restricted 2B Expression was detected in the ventral horns and at lower levels in the ventricular layer.

Specimen 2E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: forelimb pre-cartilage condensation Present 2E

Specimen 3B: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: dermis Present Regionally restricted 3B Expression was confined to a tight band of dermal mesenchymal cells just below the epidermis.
TS24: vibrissa Present Regionally restricted 3B Expression was detected in the dermal papilla but was not detected in the hair bulb.
TS24: vibrissa bulb Absent 3B

Specimen 3D: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: dermis Present Regionally restricted 3D Expression was confined to a tight band of dermal mesenchymal cells just below the epidermis.

Specimen 4B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lung mesenchyme Present 4B

Specimen 4E: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: lung mesenchyme Weak 4E

Specimen 5B: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: esophagus mesenchyme Present 5B
TS24: trachea mesenchyme Present 5B

Specimen 5E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: stomach mesenchyme Present 5E

Specimen 5H: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: stomach mesenchyme Present 5H

Specimen 6B: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: dermatome Present 6B
TS17: esophagus mesenchyme Present 6B
TS17: sclerotome Present 6B
TS17: trachea mesenchyme Present 6B
TS17: myotome Absent 6B
TS17: future spinal cord Present Regionally restricted 6B Expression was detected in the ventral horns and at lower levels in the ventricular layer.

Specimen 6E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: esophagus mesenchyme Present 6E
TS20: trachea mesenchyme Present 6E
TS20: sclerotome Present Regionally restricted 6E Expression was detected in the caudal half of the sclerotome.

Specimen 7B: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: renal tubule Present 7B
TS24: Bowman's capsule of maturing renal corpuscle Present Regionally restricted 7B Expression was detected in Bowman's capsule epithelium.
TS24: mesenchyme of metanephros Present Regionally restricted 7B Expression was detected in cortical mesenchyme.

Specimen 8B: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: long bone Present Regionally restricted 8B Expression was detected in the hypertrophied cartilage, osteocytes and osteoblasts.
TS24: limb musculature Weak 8B

Specimen 8E: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: incisor enamel organ Strong Regionally restricted 8E Expression was high in the ameloblast layer.
TS24: incisor dental papilla Strong Regionally restricted 8E Abundant expression was in the odontoblast layer and the underlying mesenchyme.

Specimen 9B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: endocardial cushion Moderate 9B
TS20: cardiac muscle tissue Weak 9B
TS20: dorsal aorta Present Regionally restricted 9B Expression was detected in the endothelium and smooth muscle.

Specimen 9E: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: endocardial cushion Weak 9E
TS24: cardiac muscle tissue Weak Diffuse 9E
TS24: aorta Weak Regionally restricted 9E Expression was detected in the endothelium and smooth muscle.

Specimen 10B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future brain Present Regionally restricted 10B Uniform expression was detected in the ventricular layer throughout the developing brain.

Specimen not shown: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: brain ventricular layer Present Uniform Uniform expression was detected in the ventricular layer throughout the developing brain.

Specimen 10E: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: brain ventricular layer Present 10E
TS24: hippocampus Present 10E
TS24: hippocampal formation Present Regionally restricted 10E Expression was detected in maturing neuronal populations in the dentate gyrus.

Specimen 10H: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: brainstem Present 10H
TS24: cerebellum Present 10H

Specimen 10K: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: trigeminal ganglion Present 10K


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/17/2024
MGI 6.24
The Jackson Laboratory