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Gene Expression Data
Assay Details
Assay
Reference: J:80178 Simon AM, et al., Vascular Abnormalities in Mice Lacking the Endothelial Gap Junction Proteins connexin37 and connexin40. Dev Biol. 2002 Nov 15;251(2):206-20
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5613405
Gene symbol: Cldn5
Gene name: claudin 5
Antibody: Claudin-5 antibody (34-1600)
Detection system: Secondary antibody
Results
Specimen 4E: embryonic day 18.5; Gja4tm1Paul/Gja4tm1Paul, Gja5tm1Paul/Gja5tm1Paul (more )
Note: (F) Fourfold higher magnification image than (E).
Structure Level Pattern Image Note
TS26: blood vessel Strong Regionally restricted 4E , 4F Expression is in endothelial cells lining abnormal vascular channels and blood pools in the testis.

Specimen 4G: embryonic day 18.5 (more )
Note: (H) Fourfold higher magnification image than (G).
Structure Level Pattern Image Note
TS26: blood vessel Present Regionally restricted 4H , 4G Expression is in endothelial cells in smaller vessels dispersed throughout the testis and in testicular arteries.

Specimen 9A: embryonic day 18.5; Gja4tm1Paul/Gja4tm1Paul, Gja5tm1Paul/Gja5tm1Paul (more )
Note: Also stained for Pecam1 (assay MGI:5613404).
Structure Level Pattern Image Note
TS26: blood vessel Strong Regionally restricted 9A Expression in endothelial cells is similar as in wild-type testis.

Specimen 9C: embryonic day 18.5 (more )
Note: Also stained for Pecam1 (assay MGI:5613404).
Structure Level Pattern Image Note
TS26: blood vessel Strong Regionally restricted 9C Expression is in endothelial cells in the testis.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory