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Cd19tm1(cre/ERT2)Rsky
Targeted Allele Detail
Summary
Symbol: Cd19tm1(cre/ERT2)Rsky
Name: CD19 antigen; targeted mutation 1, Klaus Rajewsky
MGI ID: MGI:5614310
Synonyms: CD19-, CD19creERT2, CD19-CreERT2
Gene: Cd19  Location: Chr7:126007622-126014061 bp, - strand  Genetic Position: Chr7, 69.01 cM, cytoband F3-F4
Alliance: Cd19tm1(cre/ERT2)Rsky page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:217520
Parent Cell Line:  HM-1 (ES Cell)
Strain of Origin:  129P2/OlaHsd-Hprt1b-m3
Mutation
description
Allele Type:    Targeted (Inducible, Null/knockout, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Cd19tm1(cre/ERT2)Rsky expression driven by 1 gene
    The cre/ERT2 fusion gene was knocked into exon 2. (J:217520)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Cd19 (mouse)
Summary of all recombinase alleles driven by Cd19.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cd19 Mutation:  60 strains or lines available
References
Original:  J:217520 Yasuda T, et al., Studying Epstein-Barr virus pathologies and immune surveillance by reconstructing EBV infection in mice. Cold Spring Harb Symp Quant Biol. 2013;78:259-63
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory