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Gene Expression Data
Assay Details
Assay
Reference: J:98302 Altick AL, et al., EphB receptor tyrosine kinases control morphological development of the ventral midbrain. Mech Dev. 2005 Apr;122(4):501-12
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5616107
Gene symbol: Sirpa
Gene name: signal-regulatory protein alpha
Antibody: P84 antibody
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to Cy3
Results
Specimen 5E: embryonic day 10.5; Ephb3tm1Kln/Ephb3tm1Kln (more )
Note: Double labeled: red - Sirpa; red - Isl1 (assay MGI:5616101).
Structure Level Pattern Image Note
TS17: midbrain Present Regionally restricted 5E Authors describe expression as marking ventral cells.
Specimen 5F: embryonic day 10.5; Ephb2tm2Paw/Ephb2tm2Paw, Ephb3tm1Kln/Ephb3tm1Kln (more )
Note: Double labeled: red - Sirpa; red - Isl1 (assay MGI:5616101).
Structure Level Pattern Image Note
TS17: midbrain Present Regionally restricted 5F Expanded region of expression in mutants compared to wildtype embryos.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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06/12/2024
MGI 6.13 		The Jackson Laboratory