Gt(ROSA)26Sortm3.1(CAG-Cre/ERT2)Dsa
Targeted Allele Detail
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| Symbol: |
Gt(ROSA)26Sortm3.1(CAG-Cre/ERT2)Dsa |
| Name: |
gene trap ROSA 26, Philippe Soriano; targeted mutation 3.1, Dieter Saur |
| MGI ID: |
MGI:5616878 |
| Synonyms: |
R26CAG-CreERT |
| Gene: |
Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
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| Alliance: |
Gt(ROSA)26Sortm3.1(CAG-Cre/ERT2)Dsa page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:218155
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
129S/SvEv
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| Allele Type: |
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Targeted (Inducible, Recombinase) |
| Inducer: |
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tamoxifen |
| Mutation: |
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Insertion
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Gt(ROSA)26Sortm3.1(CAG-Cre/ERT2)Dsa expression driven by
1 gene
Knock-in expression driven by:
| Organism |
Driver Gene |
Note |
| chicken |
CAG |
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Mutation details: A targeting vector containing a CAG promoter and a FRT-flanked transcriptional and translational stop sequence with a neomycin resistance gene 5' of the CreERT2 expression cassette was generated. the FRT flanked stop sequence was subsequently excised by expression of flp recombinase.
(J:218155)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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CAG
(chicken)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Gt(ROSA)26Sor Mutation: |
993 strains or lines available
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| Original: |
J:218155 Schonhuber N, et al., A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer. Nat Med. 2014 Nov;20(11):1340-7 |
| All: |
3 reference(s) |
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Analysis Tools
