Cd96<tm1.1Mjs> Targeted Allele Detail MGI Mouse (MGI:5617136)

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Cd96^tm1.1Mjs
Targeted Allele Detail

Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Summary

Symbol:	Cd96^tm1.1Mjs
Name:	CD96 antigen; targeted mutation 1.1, Mark J Smyth
MGI ID:	MGI:5617136
Gene:	Cd96 Location: Chr16:45856020-45940614 bp, - strand Genetic Position: Chr16, 30.45 cM, cytoband B5
Alliance:	Cd96^tm1.1Mjs page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:209990
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Mutation
description

Allele Type:		Targeted (Null/knockout)
Mutations:		Insertion, Intragenic deletion
		Mutation details: All of exons 1 and 2, including the start site, were replaced with a loxP site flanked neomycin resistance gene cassette. Subsequent cre-mediated recombination removed the neo cassette. (J:209990)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Cd96 Mutation:	43 strains or lines available

References

Original:	J:209990 Chan CJ, et al., The receptors CD96 and CD226 oppose each other in the regulation of natural killer cell functions. Nat Immunol. 2014 May;15(5):431-8
All:	4 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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