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Tg(CAG-EGFP,-Ptgs2,-hrluc)#Hahe
Transgene Detail
Summary
Symbol: Tg(CAG-EGFP,-Ptgs2,-hrluc)#Hahe
Name: transgene insertion, Harvey R Herschman
MGI ID: MGI:5617514
Transgene: Tg(CAG-EGFP,-Ptgs2,-hrluc)#Hahe  Location: unknown  
Alliance: Tg(CAG-EGFP,-Ptgs2,-hrluc)#Hahe page
Transgene
origin
Germline Transmission:  Earliest citation of germline transmission: J:110152
Parent Cell Line:  LW1 (ES Cell)
Strain of Origin:  129S4/SvJae
Transgene
description
Transgene Type:    Transgenic (Conditional ready, Inserted expressed sequence, Reporter)
Mutation:    Insertion
 
Mutation detailsAn enhanced green fluorescent protein, a cassette with the SV40 poly-A sequence, a PGK promoter-driven neomycin-bpA cassette, and a translational/transcriptional STOP cassette were inserted in the vector between the CAG promoter and a Ptgs2 cDNA. The coding region for a humanized version of Renilla luciferase (hrluc) was connected with the Ptgs2 coding sequence by an IRES. (J:110152)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:110152 Kamei K, et al., Transgenic mouse for conditional, tissue-specific Cox-2 overexpression. Genesis. 2006 Apr;44(4):177-82
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory