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Gata3tm1.1(cre)Gmlz
Targeted Allele Detail
Summary
Symbol: Gata3tm1.1(cre)Gmlz
Name: GATA binding protein 3; targeted mutation 1.1, Guillermo M Lanuza
MGI ID: MGI:5619418
Synonyms: Gata3Cre
Gene: Gata3  Location: Chr2:9861889-9894845 bp, - strand  Genetic Position: Chr2, 6.69 cM
Alliance: Gata3tm1.1(cre)Gmlz page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:213157
Parent Cell Line:  2A (ES Cell)
Strain of Origin:  129S1/SvImJ
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Gata3tm1.1(cre)Gmlz expression driven by 1 gene
 
Mutation details: A cre recombinase gene and FRT flanked neomycin resistance cassette were inserted into exon 2 at the ATG. Flp-mediated recombination removed the selection cassette. (J:213157)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Gata3 (mouse)
Summary of all recombinase alleles driven by Gata3.
 

Expression
In Mice Carrying this Mutation: 15 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gata3 Mutation:  32 strains or lines available
References
Original:  J:213157 Zhang J, et al., V1 and v2b interneurons secure the alternating flexor-extensor motor activity mice require for limbed locomotion. Neuron. 2014 Apr 2;82(1):138-50
All:  3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory