b2b2696.2Clo Chemically induced Allele Detail MGI Mouse (MGI:5620188)

b2b2696.2Clo
Chemically induced Allele Detail

Summary

Symbol:	b2b2696.2Clo
Name:	Mutant line 2696.2; Bench to Bassinet Program (B2B/CVDC), mutation 2696, subline 2 Cecilia Lo
MGI ID:	MGI:5620188
Gene:	b2b2696.2Clo Location: unknown
Alliance:	b2b2696.2Clo page

Mutant exhibits a right aortic arch which was confirmed by ECM imaging.

Show the 11 phenotype image(s) involving this allele.

Mutation
origin

Strain of Origin:	C57BL/6J
Project Collection:	B2B/CvDC

Mutation
description

Allele Type:		Chemically induced (ENU)
Mutation:		Undefined
		Mutation details: This ENU-induced mutation was isolated in a screen at the University of Pittsburgh. It is a subline of b2b2696Clo.

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any b2b2696.2Clo Mutation:	0 strains or lines available

Notes

General Notes (Mutant 2): Summative Diagnosis:
Cardiovascular phenotypes: Atrioventricular septal defect (AVSD), left ventricular hypertrophy, right sided aortic arch, vascular ring and other aortic arch anomalies

Noncardiovascular phenotype: Craniofacial defects including micrognathia, midline facial cleft, bilateral anopthalmia, low set ears, hypoplastic thymus, renal anomalies including duplex kidneys and hydroureter

Phenotypic Similarity to Human Syndrome:
DiGeorge syndrome

References

Original:	J:175213 Lo C, Information submitted by the NHLBI Cardiovascular Development Consortium (CvDC), Bench to Bassinet Program (B2B/CvDC). MGI Direct Data Submission (B2B/CvDC). 2011-09-12;
All:	2 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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