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Stra8tm1(EGFP/cre/ERT2)Wtsi
Targeted Allele Detail
Summary
Symbol: Stra8tm1(EGFP/cre/ERT2)Wtsi
Name: stimulated by retinoic acid gene 8; targeted mutation 1, Wellcome Trust Sanger Institute
MGI ID: MGI:5621007
Synonyms: Stra8tm1(cre/ERT2)Hmgu
Gene: Stra8  Location: Chr6:34897098-34916279 bp, + strand  Genetic Position: Chr6, 15.2 cM
Alliance: Stra8tm1(EGFP/cre/ERT2)Wtsi page
Mutation
origin
Mutant Cell Line:  CEPD0059_3_C10
Germline Transmission:  Earliest citation of germline transmission: J:188991
Parent Cell Line:  JM8.N4 (ES Cell)
Strain of Origin:  C57BL/6N
Project Collection: EUCOMMTOOLS
Mutation
description
Allele Type:    Targeted (Conditional ready, Inducible, Recombinase, Reporter)
Inducer:    tamoxifen
Mutation:    Insertion
 
Stra8tm1(EGFP/cre/ERT2)Wtsi expression driven by 1 gene
 
Mutation details: According to the allele image posted by EUCOMMTOOLS in the international knockout mouse consortium site (https://www.mousephenotype.org/imits/targ_rep), exons 4 and 5 are flanked by loxP sites and a cre/ERT2-EGRP cassette preceded by a single FRT site and followed by a Rox flanked puromycin selection cassette was inserted into the intron between exons 3 and 4. (J:155845)
Inheritance:    Not Specified
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Stra8 (mouse)
Summary of all recombinase alleles driven by Stra8.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Stra8 Mutation:  36 strains or lines available
References
Original:  J:155845 Wellcome Trust Sanger Institute, Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2010;
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory