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Plxnd1tm2(EGFP/cre/ERT2)Wtsi
Targeted Allele Detail
Summary
Symbol: Plxnd1tm2(EGFP/cre/ERT2)Wtsi
Name: plexin D1; targeted mutation 2, Wellcome Trust Sanger Institute
MGI ID: MGI:5629433
Synonyms: Plxnd1tm2(cre/ERT2)Hmgu
Gene: Plxnd1  Location: Chr6:115931772-115971966 bp, - strand  Genetic Position: Chr6, 53.72 cM
Alliance: Plxnd1tm2(EGFP/cre/ERT2)Wtsi page
Mutation
origin
Mutant Cell Line:  CEPD0086_4_G06
Germline Transmission:  Earliest citation of germline transmission: J:188991
Parent Cell Line:  JM8.N4 (ES Cell)
Strain of Origin:  C57BL/6N
Project Collection: EUCOMMTOOLS
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase, Reporter)
Inducer:    tamoxifen
Mutation:    Insertion
 
Plxnd1tm2(EGFP/cre/ERT2)Wtsi expression driven by 1 gene
 
Mutation details: According to the construct image presented by The International Mouse Knockout Consortium this allele has a single FRT site, an engrailed 2 splice acceptor site, an EGFP-cre/ERT2 cassette and a neomycin selection cassette that is driven by an automonous promoter all inserted in the intron between exons 9 and 10 and one loxP sequence inserted in the intron between exons 13 and 14. (J:155845)
Inheritance:    Not Specified
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Plxnd1 (mouse)
Summary of all recombinase alleles driven by Plxnd1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Plxnd1 Mutation:  87 strains or lines available
References
Original:  J:155845 Wellcome Trust Sanger Institute, Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2010;
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory