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Pou4f2tm1.1(cre)Tcba
Targeted Allele Detail
Summary
Symbol: Pou4f2tm1.1(cre)Tcba
Name: POU domain, class 4, transcription factor 2; targeted mutation 1.1, Tudor Constantin Badea
MGI ID: MGI:5629683
Synonyms: Brn3bCKOCre
Gene: Pou4f2  Location: Chr8:79159639-79163274 bp, - strand  Genetic Position: Chr8, 36.99 cM, cytoband F1-F5
Alliance: Pou4f2tm1.1(cre)Tcba page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:215125
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, Recombinase)
Mutation:    Insertion
 
Pou4f2tm1.1(cre)Tcba expression driven by 1 gene
 
Mutation details: The targeting construct introduced into the 3'UTR three polyadenylation squences, a RoxP site, a cre recombinase gene and an FRT-flanked neomycin resistance cassette. An additional RoxP site was inserted upstream of the translation start site. Flp-mediated recombination removed the selection cassette and left the coding sequence plus 3 polyadenylation sequence flanked by RoxP sites. (J:215125)
Generation of the Pou4f2tm1.1(cre)Tcba allele
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Pou4f2 (mouse)
Summary of all recombinase alleles driven by Pou4f2.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pou4f2 Mutation:  7 strains or lines available
References
Original:  J:215125 Sajgo S, et al., Dre - Cre sequential recombination provides new tools for retinal ganglion cell labeling and manipulation in mice. PLoS One. 2014;9(3):e91435
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory