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Cd4tm2(EGFP/cre/ERT2)Wtsi
Targeted Allele Detail
Summary
Symbol: Cd4tm2(EGFP/cre/ERT2)Wtsi
Name: CD4 antigen; targeted mutation 2, Wellcome Trust Sanger Institute
MGI ID: MGI:5632392
Synonyms: Cd4tm2(EGFP/cre/ERT2)Hmgu
Gene: Cd4  Location: Chr6:124841655-124865184 bp, - strand  Genetic Position: Chr6, 59.17 cM
Alliance: Cd4tm2(EGFP/cre/ERT2)Wtsi page
Mutation
origin
Mutant Cell Line:  CEPD0081_2_A02
Germline Transmission:  Earliest citation of germline transmission: J:204812
Parent Cell Line:  JM8.N4 (ES Cell)
Strain of Origin:  C57BL/6N
Project Collection: EUCOMMTOOLS
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase, Reporter)
Inducer:    tamoxifen
Mutation:    Insertion
 
Cd4tm2(EGFP/cre/ERT2)Wtsi expression driven by 1 gene
 
Mutation details: According to the allele molecular image presented by the International Knockout Mouse Consortium, this allele has one FRT site, an engrailed 2 splice acceptor sequence, an EGFP and cre/ERT2 expression cassette, and a neomycin resistance cassette inserted between exons 3 and 4. A single loxP site is inserted between exons 6 and 7. (J:155845)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Cd4 (mouse)
Summary of all recombinase alleles driven by Cd4.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cd4 Mutation:  85 strains or lines available
References
Original:  J:155845 Wellcome Trust Sanger Institute, Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2010;
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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11/12/2024
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