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Nalcntm2(EGFP/cre/ERT2)Wtsi
Targeted Allele Detail
Summary
Symbol: Nalcntm2(EGFP/cre/ERT2)Wtsi
Name: sodium leak channel, non-selective; targeted mutation 2, Wellcome Trust Sanger Institute
MGI ID: MGI:5633812
Synonyms: Nalcntm2(EGFP/cre/ERT2)Hmgu
Gene: Nalcn  Location: Chr14:123514046-123864556 bp, - strand  Genetic Position: Chr14, 66.04 cM
Alliance: Nalcntm2(EGFP/cre/ERT2)Wtsi page
Mutation
origin
Mutant Cell Line:  CEPD0086_2_G06
Germline Transmission:  Earliest citation of germline transmission: J:204812
Parent Cell Line:  JM8.N4 (ES Cell)
Strain of Origin:  C57BL/6N
Project Collection: EUCOMMTOOLS
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase, Reporter)
Inducer:    tamoxifen
Mutation:    Insertion
 
Nalcntm2(EGFP/cre/ERT2)Wtsi expression driven by 1 gene
 
Mutation details: According to the allele molecular image presented by the International Knockout Mouse Consortium, this allele has one FRT site, an engrailed 2 splice acceptor sequence, an EGFP and cre/ERT2 expression cassette, and a neomycin resistance cassette inserted in the intron between exons 4 and 5. A single loxP site is inserted in intron 6. (J:155845)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Nalcn (mouse)
Summary of all recombinase alleles driven by Nalcn.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nalcn Mutation:  116 strains or lines available
References
Original:  J:155845 Wellcome Trust Sanger Institute, Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2010;
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory