About   Help   FAQ
Tbx2tm1(EGFP/cre/ERT2)Wtsi
Targeted Allele Detail
Summary
Symbol: Tbx2tm1(EGFP/cre/ERT2)Wtsi
Name: T-box 2; targeted mutation 1, Wellcome Trust Sanger Institute
MGI ID: MGI:5633849
Synonyms: Tbx2tm1(EGFP/cre/ERT2)Hmgu
Gene: Tbx2  Location: Chr11:85723441-85732774 bp, + strand  Genetic Position: Chr11, 51.34 cM
Alliance: Tbx2tm1(EGFP/cre/ERT2)Wtsi page
Mutation
origin
Mutant Cell Line:  CEPD0034_4_F07
Germline Transmission:  Earliest citation of germline transmission: J:204812
Parent Cell Line:  JM8.N4 (ES Cell)
Strain of Origin:  C57BL/6N
Project Collection: EUCOMMTOOLS
Mutation
description
Allele Type:    Targeted (Conditional ready, Inducible, Recombinase, Reporter)
Inducer:    tamoxifen
Mutation:    Insertion
 
Tbx2tm1(EGFP/cre/ERT2)Wtsi expression driven by 1 gene
 
Mutation details: According to the allele molecular image presented by the International Knockout Mouse Consortium, this allele has loxP sites flanking exon 2, and inserted into the intron between exons 1 and 2 is one FRT site, an engrailed 2 splice acceptor sequence, an EGFP and cre/ERT2 expression cassette, and a Rox flanked puromycin resistance cassette. (J:155845)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Tbx2 (mouse)
Summary of all recombinase alleles driven by Tbx2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Tbx2 Mutation:  29 strains or lines available
References
Original:  J:155845 Wellcome Trust Sanger Institute, Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2010;
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory