Ucp1tm1.1(EGFP/cre/ERT2)Wtsi
Targeted Allele Detail
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Symbol: |
Ucp1tm1.1(EGFP/cre/ERT2)Wtsi |
Name: |
uncoupling protein 1 (mitochondrial, proton carrier); targeted mutation 1, Wellcome Trust Sanger Institute |
MGI ID: |
MGI:5633869 |
Synonyms: |
Ucp1tm1.1(EGFP/cre/ERT2)Hmgu |
Gene: |
Ucp1 Location: Chr8:84016981-84025081 bp, + strand Genetic Position: Chr8, 39.65 cM
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Alliance: |
Ucp1tm1.1(EGFP/cre/ERT2)Wtsi page
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Mutant Cell Line: |
CEPD0007_1_C12 |
Germline Transmission: |
Earliest citation of germline transmission:
J:204812
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Parent Cell Line: |
JM8.N4 (ES Cell)
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Strain of Origin: |
C57BL/6N
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Project Collection: |
EUCOMMTOOLS
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Allele Type: |
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Targeted (Conditional ready, Inducible, Recombinase, Reporter) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Ucp1tm1.1(EGFP/cre/ERT2)Wtsi expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Ucp1 (MGI:98894) |
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Mutation details: According to the allele molecular image presented by the International Knockout Mouse Consortium, this allele has loxP sites flanking exon 2, and inserted into the intron between exons 1 and 2 is one FRT site, an engrailed 2 splice acceptor sequence, an EGFP and cre/ERT2 expression cassette, and a single Rox site remaining after a flanked puromycin resistance cassette removal.
(J:155845)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Ucp1
(mouse)
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Original: |
J:155845 Wellcome Trust Sanger Institute, Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2010; |
All: |
2 reference(s) |
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