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Prlhtm1(cre)Smln
Targeted Allele Detail
Summary
Symbol: Prlhtm1(cre)Smln
Name: prolactin releasing hormone; targeted mutation 1, Simon M Luckman
MGI ID: MGI:5634277
Synonyms: PrRP-Cre
Gene: Prlh  Location: Chr1:90880830-90881749 bp, + strand  Genetic Position: Chr1, 45.81 cM
Alliance: Prlhtm1(cre)Smln page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:215557
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Prlhtm1(cre)Smln expression driven by 1 gene
    An IRES-cre was inserted downstream of the endogenous STOP codon in exon 2. (J:215557)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Prlh (mouse)
Summary of all recombinase alleles driven by Prlh.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Prlh Mutation:  7 strains or lines available
References
Original:  J:215557 Dodd GT, et al., The thermogenic effect of leptin is dependent on a distinct population of prolactin-releasing peptide neurons in the dorsomedial hypothalamus. Cell Metab. 2014 Oct 7;20(4):639-49
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory